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Browse our GINS Complex Subunit 2 (Psf2 Homolog) Proteins (GINS2)

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GINS Complex Subunit 2 (Psf2 Homolog) Proteins (GINS2)
On www.antibodies-online.com are 12 GINS Complex Subunit 2 (Psf2 Homolog) (GINS2) Proteins from 4 different suppliers available. Additionally we are shipping GINS Complex Subunit 2 (Psf2 Homolog) Antibodies (30) and many more products for this protein. A total of 48 GINS Complex Subunit 2 (Psf2 Homolog) products are currently listed.
Synonyms:
2210013I18Rik, 4833427B12Rik, AI323585, HSPC037, Pfs2, PSF2, RGD1311055, si:dkey-265o13.3, zgc:112262
list all proteins Gene Name GeneID UniProt
GINS2 51659 Q9Y248
GINS2 272551 Q9D600
Rat GINS2 GINS2 292058  

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GINS Complex Subunit 2 (Psf2 Homolog) Proteins (GINS2) by Origin

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More Proteins for GINS Complex Subunit 2 (Psf2 Homolog) Interaction Partners

Human GINS Complex Subunit 2 (Psf2 Homolog) (GINS2) interaction partners

  1. silencing of GINS2 in triple negative breast cancer cells caused dramatic decrease of matrix metalloproteinase-9 (MMP9 (show MMP9 Proteins)).

  2. High GINS2 transcript level is associated with endocrine therapy resistance in beast cancer.

  3. On the contrary, after HL60 cells were infected by recombinant adenovirus vector which contained GINS2 gene, we observed that over-expression of GINS2 could promote HL-60 cell proliferation.

  4. GINS2 plays an important role in apoptosis and may function via the p38MAPK (show MAPK14 Proteins) signaling pathway.

  5. Data show that using a 200-nt primed circular DNA substrate, the combined action of DNA polymerase epsilon and the Cdc45 (show CDC45 Proteins)/Mcm2-7 (show MCM2 Proteins)/GINS (CMG (show CASK Proteins) complex) leads to the formation of products >10 kb in length.

  6. Data suggest that GINS2 to be associated with the aggressive characteristics of a subgroup of breast cancers in vivo.

Xenopus laevis GINS Complex Subunit 2 (Psf2 Homolog) (GINS2) interaction partners

  1. Data show that MRE11- and RAD51-dependent fork repair leading to reloading of the GINS onto the MCM-CDC45 complex still engaged with the DNA could be sufficient to restore a functional CDC45-MCM-GINS (CMG) helicase complex.

GINS Complex Subunit 2 (Psf2 Homolog) (GINS2) Protein Profile

Protein Summary

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4\; MIM 610611), Psf1 (GINS1\; MIM 610608), Psf2, and Psf3 (GINS3\; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005

Alternative names and synonyms associated with GINS Complex Subunit 2 (Psf2 Homolog) (GINS2)

  • DNA replication complex GINS protein PSF2 (Psf2)
  • GINS complex subunit 2 (Psf2 homolog) (gins2)
  • DNA replication complex GINS protein PSF2 (psf2)
  • GINS complex subunit 2 (gins2)
  • GINS complex subunit 2 (Psf2 homolog) (GINS2)
  • GINS complex subunit 2 (Psf2 homolog) (Gins2)
  • similar to C terminus of S. cerevisiae PSF2 (YJL072C) component of the GINS complex involved in DNA replication initiation; rest of gene upstream of small intron (PSF2)
  • 2210013I18Rik protein
  • 4833427B12Rik protein
  • AI323585 protein
  • HSPC037 protein
  • Pfs2 protein
  • PSF2 protein
  • RGD1311055 protein
  • si:dkey-265o13.3 protein
  • zgc:112262 protein

Protein level used designations for GINS2

DNA replication complex GINS protein PSF2 , potential GINS DNA replication initiation complex subunit

GENE ID SPECIES
408755 Apis mellifera
549769 Xenopus (Silurana) tropicalis
100195188 Salmo salar
554146 Danio rerio
51659 Homo sapiens
609436 Canis lupus familiaris
100299171 Bos taurus
272551 Mus musculus
292058 Rattus norvegicus
444053 Xenopus laevis
3647546 Candida albicans SC5314
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