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Browse our FOXA2 Proteins (FOXA2)

Full name:
Forkhead Box A2 Proteins (FOXA2)
On www.antibodies-online.com are 7 Forkhead Box A2 (FOXA2) Proteins from 3 different suppliers available. Additionally we are shipping FOXA2 Antibodies (191) and FOXA2 Kits (4) and many more products for this protein. A total of 217 FOXA2 products are currently listed.
Synonyms:
ax, axl, fkd1, FOXA2, FoxA2-A, FoxA2a, Hnf-3b, HNF-3BETA, HNF3-beta, Hnf3b, HNF3beta, ik:tdsubc_2g8, Tcf-3b, Tcf3b, tdsubc_2g8, wu:fe05g04, xbeta-1, xFD-3, xx:tdsubc_2g8
list all proteins Gene Name GeneID UniProt
FOXA2 3170 Q9Y261
FOXA2 15376 P35583
FOXA2 25099 P32182

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FOXA2 Proteins (FOXA2) by Origin

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More Proteins for FOXA2 Interaction Partners

Human Forkhead Box A2 (FOXA2) interaction partners

  1. FOXA2 identified as a novel tumor suppressor in pancreatic cancer. It is regulated directly by miR (show MLXIP Proteins)-199a.

  2. This study used combined immunohistochemical staining for a marker of hepatic commitment and specification (FOXA2 [Forkhead box A2]), hepatocyte maturation (Albumin (show ALB Proteins) and HepPar1), and features of bile ducts (CK19 (show KRT19 Proteins) [cytokeratin 19 (show KRT19 Proteins)]) to identify lineages of stem cells differentiating toward the hepatocytic or bile ductular compartments of end-stage cirrhotic human liver.

  3. Foxa2, a novel protein partner of the tumour suppressor menin (show MEN1 Proteins), is deregulated in mouse and human MEN1 (show MEN1 Proteins) glucagonomas.

  4. The pattern of FOXA2 mutations and expression in tumors suggests complex regulation and a haploinsufficient or dominant-negative tumor suppressor function.

  5. Study demonstrated downregulation of expression of pancreatic master genes SOX9 (show SOX9 Proteins), FOXA2, and GATA4 (show GATA4 Proteins) (2-, 5-, and 4-fold, respectively) and in PANC1 pancreatic cancer cell line stimulated with TGFbeta1 (show TGFB1 Proteins)

  6. The definitive endoderm and foregut endoderm differentiation capabilities of Wnt (show WNT2 Proteins) pathway-modulated cells were determined based on the expression levels of the endodermal transcription factors SOX17 (show SOX17 Proteins) and FOXA2 and those of the transcription activator GATA4 (show GATA4 Proteins) and the alpha-fetoprotein (AFP (show AFP Proteins)) gene, respectively.

  7. Meta-analysis results clearly point to an important role of FOXA1 (show FOXA1 Proteins) and FOXA2 gene regulatory networks in the etiology of Alzheimer's disease

  8. The ratio of FoxA1 (show FOXA1 Proteins) to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor (show ASH1L Proteins) LSH (show HELLS Proteins)

  9. Loss of Interdependent Binding by the FoxO1 (show FOXO1 Proteins) and FoxA1 (show FOXA1 Proteins)/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Proteins)-sensitive Genes.

  10. FoxA1 (show FOXA1 Proteins), FoxA2, and LIPG (show LIPG Proteins) control the uptake of extracellular lipids for breast cancer growth.

Zebrafish Forkhead Box A2 (FOXA2) interaction partners

  1. in FoxA2-FoxA3 (show FOXA3 Proteins) double morphants, precursors of axial tissues are correctly induced at early gastrula stage, but their dorsal midline identity is not maintained during development

  2. Foxa2 is required for induction and/or patterning of several distinct cell types in the ventral CNS.

Xenopus laevis Forkhead Box A2 (FOXA2) interaction partners

  1. HNF3beta target genes function to limit the extent of mesoderm formation in the Xenopus gastrula.

Mouse (Murine) Forkhead Box A2 (FOXA2) interaction partners

  1. Foxa2, a novel protein partner of the tumour suppressor menin (show MEN1 Proteins), is deregulated in mouse and human MEN1 (show MEN1 Proteins) glucagonomas.

  2. our study demonstrates that Foxa2 is required in both alpha and beta cells for maintaining appropriate glucagon (show GCG Proteins) and insulin (show INS Proteins) levels and for keeping glucose homeostasis.

  3. Loss of Interdependent Binding by the FoxO1 (show FOXO1 Proteins) and FoxA1 (show FOXA1 Proteins)/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin (show INS Proteins)-sensitive Genes.

  4. FoxA1 (show FOXA1 Proteins), FoxA2, and LIPG (show LIPG Proteins) control the uptake of extracellular lipids for breast cancer growth.

  5. The authors show herein that Nurr1 (show NR4A2 Proteins) and Foxa2 interact to protect midbrain dopaminergic neurons against various toxic insults, but their expression is lost during aging and degenerative processes.

  6. Authors identified thousands of enhancers that are bound by the master regulators HNF4A (show HNF4A Proteins) and FOXA2 in a differentiation-dependent manner, subject to chromatin remodeling, and associated with differentially expressed target genes.

  7. this study demonstrates that SIRT1 (show SIRT1 Proteins) controls the acetylation level of FOXA2 in a nutrient-dependent manner and in times of nutrient shortage the interaction between SIRT1 (show SIRT1 Proteins) and FOXA2 is reduced.

  8. Hh signaling upregulated FOXA2, which induced expression of MUC2 (show MUC2 Proteins), an intestinal mucin (show SLC13A2 Proteins) found in Barrett's esophagus, and the MUC2 (show MUC2 Proteins)-processing protein AGR2 (show AGR2 Proteins)

  9. through interactions with FoxA2, Arx positively regulates Shh expression in the floor plate, and Shh signaling in turn activates Nkx2.2, which suppresses Arx expression.

  10. studies have identified a novel TXNIP (show TXNIP Proteins)/miR (show MLXIP Proteins)-124a/FoxA2/IAPP (show IAPP Proteins) signaling cascade linking the critical beta-cell signaling pathways of TXNIP (show TXNIP Proteins) and IAPP (show IAPP Proteins)

FOXA2 Protein Profile

Protein Summary

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.

Alternative names and synonyms associated with FOXA2

  • forkhead box A2 (foxa2)
  • forkhead box A2 (FOXA2)
  • forkhead box A2 (Foxa2)
  • ax protein
  • axl protein
  • fkd1 protein
  • FOXA2 protein
  • FoxA2-A protein
  • FoxA2a protein
  • Hnf-3b protein
  • HNF-3BETA protein
  • HNF3-beta protein
  • Hnf3b protein
  • HNF3beta protein
  • ik:tdsubc_2g8 protein
  • Tcf-3b protein
  • Tcf3b protein
  • tdsubc_2g8 protein
  • wu:fe05g04 protein
  • xbeta-1 protein
  • xFD-3 protein
  • xx:tdsubc_2g8 protein

Protein level used designations for Forkhead Box A2 Proteins (FOXA2)

fork head transcription factor FoxA2 , forkhead box protein A2 , forkhead box A2 , HNF-3-beta , HNF-3B , TCF-3B , hepatic nuclear factor-3-beta , hepatocyte nuclear factor 3, beta , hepatocyte nuclear factor 3-beta , transcription factor 3B , axial protein , etID309811.17 , hnf3b , mol , monorail , HNF-3-beta-A , HNF3-beta homolog A , HNF3-beta-A , Hepatocyte nuclear factor 3-beta homolog A , fork head domain-related protein 3 , forkhead box protein A2-A , xHNF3-beta-A , hepatocyte nuclear factor 3 beta , hepatocyte nuclear factor 3 beta (winged helix transcription factor) , hepatocyte nuclear factor-3 beta , hepatocyte nuclear factor-3beta , transcription factor Foxa2

GENE ID SPECIES
395063 Xenopus (Silurana) tropicalis
701771 Macaca mulatta
3170 Homo sapiens
30126 Danio rerio
100127318 Xenopus laevis
485742 Canis lupus familiaris
503580 Bos taurus
15376 Mus musculus
25099 Rattus norvegicus
395539 Gallus gallus
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