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polymorphisms in the ADCY9 gene are significantly associated with asthma and/or allergy markers
The stronger TNF-alpha (show TNF Proteins) responses in young males compared to females may be partly associated with male-specific down-regulation of ADCY7 (show Adcy7 Proteins) and ADCY9.
The effects of dalcetrapib on atherosclerotic outcomes are determined by correlated polymorphisms in the ADCY9 gene.
The importance of miR (show MLXIP Proteins)-181a-mediated AC9 downregulation in acute promyelocytic leukemia (show PML Proteins), is reported.
Data indicate that adenylyl cyclase 9 (AC9) transcript is a direct target of miR (show MLXIP Proteins)-181b.
in heart, Yotiao brings together PKA, PP1 (show PPA1 Proteins), PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.
The HIV-1 regulatory protein Tat (show TAT Proteins) was shown to inhibit the activity of adenylyl cyclase in rat microglial cells.
blocking glycosylation of AC9 significantly attenuates Galpha (show SUCLG1 Proteins)(s) stimulation.
in heart, Yotiao brings together PKA, PP1 (show PPP1CC Proteins), PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.
miR (show MLXIP Proteins)-142-3p regulates the production of cAMP by targeting adenylyl cyclase (AC) 9 messenger RNA in CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(-) T cells and CD4 (show CD4 Proteins)(+)CD25 (show IL2RA Proteins)(+) T(REG (show KCNH2 Proteins)) cells.
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.
adenylate cyclase 9
, adenylate cyclase type 9-like
, ATP pyrophosphate-lyase 9
, adenylate cyclase type 9
, adenylate cyclase type IX
, adenylyl cyclase 9
, type IX ATP pyrophosphate-lyase
, adenylyl cyclase type 10
, adenylyl cyclase type IX