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Browse our AFAP1L2 Proteins (AFAP1L2)

Full name:
Actin Filament Associated Protein 1-Like 2 Proteins (AFAP1L2)
On are 5 Actin Filament Associated Protein 1-Like 2 (AFAP1L2) Proteins from 3 different suppliers available. Additionally we are shipping AFAP1L2 Antibodies (35) and AFAP1L2 Kits (9) and many more products for this protein. A total of 52 AFAP1L2 products are currently listed.
AU041783, C86904, KIAA1914, mKIAA1914, RGD1310668, XB130
list all proteins Gene Name GeneID UniProt
AFAP1L2 84632 Q8N4X5
AFAP1L2 226250 Q5DTU0
Rat AFAP1L2 AFAP1L2 292130  

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AFAP1L2 Proteins (AFAP1L2) by Origin

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More Proteins for AFAP1L2 Interaction Partners

Human Actin Filament Associated Protein 1-Like 2 (AFAP1L2) interaction partners

  1. XB130 is a mediator for nicotine-derived nitrosamine ketone-induced cell migration through its translocation to cell motility related microfilamentous cellular structures.

  2. XB130 could be useful as a prognostic marker of recurrence-free and overall survival in invasive ductal breast cancer, as well as for the response to chemotherapy.

  3. This is the first study to reveal that XB130 overexpression may be related to the prediction of metastasis potency and poor prognosis for osteosarcoma patients

  4. Results showed significant interaction between variants at TERF1 (show TERF1 Proteins) and AFAP1L2 loci. Given the key role of TERF1 (show TERF1 Proteins) in telomere biology and its physical interaction with AFAP1L2, these results support a role for telomere dysfunction in melanoma development.

  5. High XB130 expression is associated with pancreatic ductal adenocarcinoma.

  6. XB130 enhances cell motility and invasiveness by modulating the epithelial-mesenchymal transition-like process.

  7. High nuclear expression of XB130 is associated with esophageal squamous cell carcinoma.

  8. XB130 could promote growth of cancer cells by regulating expression of tumor suppressive miRNAs and their targeted genes.

  9. XB130 is a substrate of multiple protein tyrosine kinases, and it can regulate cell proliferation and survival through modulating selected down-stream signals of PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway

  10. reduced XB130 protein expression is a prognostic biomarker for shorter survival and a higher recurrence rate in patients with gastric cancer

AFAP1L2 Protein Profile

Protein Summary

May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity).

Alternative names and synonyms associated with AFAP1L2

  • actin filament associated protein 1-like 2 (AFAP1L2)
  • actin filament associated protein 1-like 2 (Afap1l2)
  • AU041783 protein
  • C86904 protein
  • KIAA1914 protein
  • mKIAA1914 protein
  • RGD1310668 protein
  • XB130 protein

Protein level used designations for AFAP1L2

AFAP1-like protein 2 , CTB-1144G6.4 , actin filament-associated protein 1-like 2 , phosphatidylinositol 3-kinase-associated protein

84632 Homo sapiens
226250 Mus musculus
292130 Rattus norvegicus
615436 Bos taurus
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