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Browse our Adaptor-Related Protein Complex 2, mu 1 Subunit Proteins (AP2M1)

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Adaptor-Related Protein Complex 2, mu 1 Subunit Proteins (AP2M1)
On www.antibodies-online.com are 16 Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) Proteins from 5 different suppliers available. Additionally we are shipping Adaptor-Related Protein Complex 2, mu 1 Subunit Antibodies (134) and Adaptor-Related Protein Complex 2, mu 1 Subunit Kits (24) and many more products for this protein. A total of 181 Adaptor-Related Protein Complex 2, mu 1 Subunit products are currently listed.
Synonyms:
AP2M1, ap2m1-a, Ap50, cb34, Clapm1, dpy-23, mu2, sb:cb34, wu:fa97a10, zgc:55711, zgc:56643, zgc:85653
list all proteins Gene Name GeneID UniProt
AP2M1 1173 Q96CW1
AP2M1 11773 P84091
AP2M1 116563 P84092

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Adaptor-Related Protein Complex 2, mu 1 Subunit Proteins (AP2M1) by Origin

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More Proteins for Adaptor-Related Protein Complex 2, mu 1 Subunit Interaction Partners

Human Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) interaction partners

  1. BMCC1 (show PRUNE2 Proteins) is an AP-2 (show GTF3A Proteins) associated endosomal protein in prostate cancer cells.

  2. We identify dynamin and the EAP-binding alpha-adaptin appendage domain of the AP2 adaptor as switches in a regulated, multistep maturation process and provide direct evidence for a molecular checkpoint in clathrin mediated endocytosis.

  3. a conserved heretofore unrecognized YXXPhi motif (Phi is a bulky hydrophobic residue) within the core protein. This motif is homologous to sorting signals within host cargo proteins known to mediate binding of AP2M1

  4. Arkadia (show RNF111 Proteins) complexes with clathrin adaptor AP2 (show GTF3A Proteins) mu2 subunit and regulates EGF (show EGF Proteins) signalling.

  5. These results suggest that AP-2 (show GTF3A Proteins) is essential for endocytic clathrin coated-pit (show IRF6 Proteins) and coated-vesicle formation.

  6. multiple interactions between PIPKI gamma-p90 and AP-2 lead to spatiotemporally controlled PI(4,5)P(2) synthesis during clathrin-mediated synaptic vesicle endocytosis.

  7. V1H can function as an adaptor for interactions between Nef and AP-2 (show GTF3A Proteins).

  8. direct association of the adaptor complex 2 with a G protein-coupled receptor has not been reported so far and might represent a common mechanism underlying clathrin-mediated receptor endocytosis

  9. Results indicate that AP-2 is not essential for clathrin-coated vesicle formation at the plasma membrane, but that it is one of several endocytic adaptors required for the uptake of certain cargo proteins.

  10. AP-2 (show GTF3A Proteins) is completely dependent on both (D/E)xxxL(L/I) motifs and 20 YxxO motifs signals to mediate TCR internalization; AP2M1 interacts with tyrosine in CD3delta (show CD3D Proteins) and CD3gamma

Mouse (Murine) Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) interaction partners

  1. Binding of AP-2 (show TFAP2A Proteins) to otoferlin facilitates replenishment of release sites, for example, via speeding AZ clearance of exocytosed material, in addition to a role of AP-2 (show TFAP2A Proteins) in synaptic vesicle reformation.

  2. Data shsow that mutation of residues at the DEP-mu2 contact or in the tyrosine motif reduce affinity of Dvl2 (show DVL2 Proteins) for mu2.

Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1) Protein Profile

Protein Summary

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1)

  • adaptor-related protein complex 2, mu 1 subunit (AP2M1)
  • adaptor-related protein complex 2, mu 1 subunit, a (ap2m1a)
  • adaptor-related protein complex 2, mu 1 subunit, b (ap2m1b)
  • adaptor protein complex AP-2, mu1 (ap2m1)
  • AP-2 complex subunit mu-1 (ap2m1)
  • adaptor-related protein complex 2, mu 1 subunit (LOC100349480)
  • adaptor-related protein complex 2, mu 1 subunit (LOC100350578)
  • clathrin coat assembly protein AP50 (cgd8_950)
  • clathrin coat assembly protein ap50 (PY06523)
  • clathrin coat assembly protein AP50 (PVX_118455)
  • clathrin coat assembly protein AP50 (PVX_123590)
  • clathrin coat assembly protein AP50 (CpipJ_CPIJ003697)
  • adaptor-related protein complex 2, mu 1 subunit (Ap2m1)
  • adaptor-related protein complex 2, mu 1 subunit (ap2m1)
  • AP2M1 protein
  • ap2m1-a protein
  • Ap50 protein
  • cb34 protein
  • Clapm1 protein
  • dpy-23 protein
  • mu2 protein
  • sb:cb34 protein
  • wu:fa97a10 protein
  • zgc:55711 protein
  • zgc:56643 protein
  • zgc:85653 protein

Protein level used designations for AP2M1

AP-2 complex subunit mu-1-A , AP-2 complex subunit mu-A , AP-2 mu-2 chain A , AP-2 mu-A chain , adaptor protein complex AP-2, mu1 , clathrin assembly protein complex 2 medium chain A , clathrin coat assembly protein AP50-A , clathrin coat-associated protein AP50-A , mu2-adaptin-A , plasma membrane adaptor AP-2 50 kDa protein A , AP-2 complex subunit mu-1-B , AP-2 complex subunit mu-B , AP-2 mu-2 chain B , AP-2 mu-B chain , clathrin assembly protein complex 2 medium chain B , clathrin coat assembly protein AP50-B , clathrin coat-associated protein AP50-B , mu2-adaptin-B , plasma membrane adaptor AP-2 50 kDa protein B , AP-2 complex subunit mu , AP-2 complex subunit mu-1 , AP-2 mu chain , AP-2 mu-2 chain , clathrin assembly protein complex 2 medium chain , clathrin coat assembly protein AP50 , clathrin coat-associated protein AP50 , mu2-adaptin , plasma membrane adaptor AP-2 50 kDa protein , adaptor-related protein complex 2, mu 1 subunit , AP-2 complex subunit mu-like , clathrin coat assembly protein ap50 , AP-2 mu 2 chain , HA2 50 kDA subunit , adapter-related protein complex 2 mu subunit , adaptin-mu2 , adaptor protein complex AP-2 subunit mu , clathrin adaptor complex AP2, mu subunit , clathrin coat adaptor protein AP50 , clathrin-associated/assembly/adaptor protein, medium 1 , plasma membrane adaptor AP-2 50kDA protein , adaptor-related protein complex AP-2, mu1 , clathrin-associated AP-2 , coat assembly protein complex 50 kD , HA2 50 kDa subunit

GENE ID SPECIES
100626761 Sus scrofa
321051 Danio rerio
394001 Danio rerio
394572 Xenopus (Silurana) tropicalis
703554 Macaca mulatta
736431 Pan troglodytes
100058961 Equus caballus
100195111 Salmo salar
100301824 Oncorhynchus mykiss
100349480 Oryctolagus cuniculus
100350578 Oryctolagus cuniculus
100385882 Callithrix jacchus
100580778 Nomascus leucogenys
3374633 Cryptosporidium parvum Iowa II
3792524 Plasmodium yoelii yoelii 17XNL
5475282 Plasmodium vivax Sal-1
5476588 Plasmodium vivax Sal-1
6035307 Culex quinquefasciatus
1173 Homo sapiens
11773 Mus musculus
116563 Rattus norvegicus
517446 Bos taurus
770246 Gallus gallus
607139 Canis lupus familiaris
100174724 Pongo abelii
380497 Xenopus laevis
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