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Browse our Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) ELISA Kits

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Amyloid beta (A4) Precursor-Like Protein 2 ELISA Kits (APLP2)
On www.antibodies-online.com are 11 Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) ELISA Kits from 8 different suppliers available. Additionally we are shipping Amyloid beta (A4) Precursor-Like Protein 2 Antibodies (90) and Amyloid beta (A4) Precursor-Like Protein 2 Proteins (9) and many more products for this protein. A total of 116 Amyloid beta (A4) Precursor-Like Protein 2 products are currently listed.
Synonyms:
AI790698, APLP-2, APLP2, aplp2 A, aplp2 B, Apph, APPL2, CDEBP, MGC86389, si:dkey-11k4.3, WALPLP2
list all ELISA KIts Gene Name GeneID UniProt
APLP2 334 Q06481
APLP2 11804 Q06335
APLP2 64312  

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Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) ELISA Kits by Reactivity

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More ELISA Kits for Amyloid beta (A4) Precursor-Like Protein 2 Interaction Partners

Zebrafish Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. these results indicate the Appa (show APP ELISA Kits)-RFP (show MKRN1 ELISA Kits) and Aplp2 fusion proteins are likely secreted from the central nervous system and accumulate in the embryonic veins independent of blood flow.

Human Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  2. Data show that amyloid precursor-like protein 2 (APLP2) expression is elevated in pancreatic cancer metastases.

  3. We conclude that PCSK9 (show PCSK9 ELISA Kits) enhances the degradation of the LDLR (show LDLR ELISA Kits) independently of either APLP2 or sortilin (show SORT1 ELISA Kits) both ex vivo and in mice.

  4. APLP1 (show APLP1 ELISA Kits) and APLP2, behave similarly to APP (show APP ELISA Kits) in that they both associate with assembled NMDA receptors in the endoplasmic reticulum

  5. our discoveries establish a role for APLP2 in the growth of pancreatic cancer cells and show that inhibitors preventing APLP2 cleavage reduce the viability of pancreatic cancer cells.

  6. amyloid precursor protein-like (show APP ELISA Kits) protein-2, but not amyloid precursor protein (show APP ELISA Kits), is involved in mediating postendocytic delivery of PCSK9 (show PCSK9 ELISA Kits) to lysosomes and is therefore important for PCSK9 (show PCSK9 ELISA Kits) function

  7. Aberrant enhancement of YWK-II/APLP2 by nuclear export of Bat3 (show BAT3 ELISA Kits) may play a role in cancer development by inhibiting cell apoptosis.

  8. APP (show APP ELISA Kits) and its mammalian homologs, amyloid precursor-like proteins APLP1 (show APLP1 ELISA Kits) and APLP2, participate under physiological conditions via trans-cellular dimerization in synaptogenesis.

  9. APLP-2 (and APLP1 (show APLP1 ELISA Kits)) are capable of activating gene transcription via binding to Mint3 (show APBA3 ELISA Kits).

  10. Regulation of major histocompatibility complex class I molecule expression on cancer cells by amyloid precursor-like protein 2.

Mouse (Murine) Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. These data support the notion that APP (show APP ELISA Kits) and APLP2 facilitate transmitter release, likely through the interaction with the neurotransmitter release machinery.

  2. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  3. Study provides compelling evidence for an essential role of both APP (show APP ELISA Kits) and APLP2 for neuronal and synaptic morphology as well as hippocampal function and suggest an acute and specific function of endogenous APPsalpha to facilitate synaptic plasticity

  4. The study investigates the subcellular distribution patterns of the metal ions Cu, Zn, Fe, and Ca in individual neurons derived from APP (show APP ELISA Kits) and APLP2 knockout mice brains to further define their role in metal homeostasis.

  5. This study further highlights the distinct and essential role of APLP2 at NMJ synapses that cannot be compensated by APP (show APP ELISA Kits).

  6. Amyloid precursor protein (APP)/APP-like (show APP ELISA Kits) protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome

  7. The study investigated copper, iron, zinc and manganese levels in APP (show APP ELISA Kits) and APLP-2 single knockout mice as well as homozygous:hemizygous knockout mice at 3, 12 and 18 plus months of age.

  8. Data reveal that APLP2 is specifically required for proper cell cycle exit of neuronal progenitors, and thus has a distinct role in priming cortical progenitors for neuronal differentiation.

  9. APLP2 and the intracellular domain of APP (show APP ELISA Kits) are not essential for coherent activity patterns in the hippocampus, but have subtle effects on synaptic plasticity and fine-tuning of network oscillations.

  10. Gain and loss of function experiments demonstrate that miR (show MLXIP ELISA Kits)-153 suppresses expression of amyloid precursor protein (APP (show APP ELISA Kits)) and APLP2.

Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antigen Profile

Antigen Summary

This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Amyloid beta (A4) Precursor-Like Protein 2 (APLP2)

  • amyloid beta (A4) precursor-like protein 2 (aplp2-b) Elisa Kit
  • amyloid beta (A4) precursor-like protein 2 (APLP2) Elisa Kit
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (APPL2) Elisa Kit
  • amyloid beta (A4) precursor-like protein 2 (aplp2) Elisa Kit
  • amyloid beta (A4) precursor-like protein 2 (Aplp2) Elisa Kit
  • AI790698 Elisa Kit
  • APLP-2 Elisa Kit
  • APLP2 Elisa Kit
  • aplp2 A Elisa Kit
  • aplp2 B Elisa Kit
  • Apph Elisa Kit
  • APPL2 Elisa Kit
  • CDEBP Elisa Kit
  • MGC86389 Elisa Kit
  • si:dkey-11k4.3 Elisa Kit
  • WALPLP2 Elisa Kit

Protein level used designations for APLP2

amyloid beta (A4) precursor-like protein 2 , amyloid-beta-like protein B , DIP13 beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , suppression of tumorigenicity 14 , amyloid-like protein 2 , DCC-interacting protein 13-beta-like , amyloid-like protein 2-like , amyloid-beta-like protein A , CDEI box-binding protein , amyloid precursor protein homolog HSD-2 , CDEBP , Amyloid protein precursor-like protein 2 , amyloid beta (A4) precursor-like protein 2-like , sperm membrane protein (YWK-II) , sperm membrane protein YWK-II

GENE ID SPECIES
431789 Xenopus laevis
452197 Pan troglodytes
479393 Canis lupus familiaris
481297 Canis lupus familiaris
718819 Macaca mulatta
741867 Pan troglodytes
785005 Bos taurus
796801 Danio rerio
100068170 Equus caballus
100072668 Equus caballus
100076773 Ornithorhynchus anatinus
100126835 Sus scrofa
100358231 Oryctolagus cuniculus
100380132 Xenopus (Silurana) tropicalis
100404192 Callithrix jacchus
100414190 Callithrix jacchus
100470064 Ailuropoda melanoleuca
100477041 Ailuropoda melanoleuca
431790 Xenopus laevis
100557178 Anolis carolinensis
334 Homo sapiens
11804 Mus musculus
64312 Rattus norvegicus
419727 Gallus gallus
100190991 Sus scrofa
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