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Browse our ADP-Ribosylation Factor 4 Proteins (ARF4)

Full name:
ADP-Ribosylation Factor 4 Proteins (ARF4)
On are 22 ADP-Ribosylation Factor 4 (ARF4) Proteins from 8 different suppliers available. Additionally we are shipping ADP-Ribosylation Factor 4 Antibodies (65) and ADP-Ribosylation Factor 4 Kits (12) and many more products for this protein. A total of 105 ADP-Ribosylation Factor 4 products are currently listed.
AA407803, ARF2
list all proteins Gene Name GeneID UniProt
ARF4 11841 Q8BSL7
ARF4 79119 P84082
ARF4 378 P18085

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ADP-Ribosylation Factor 4 Proteins (ARF4) by Origin

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Top referenced ADP-Ribosylation Factor 4 Proteins

  1. Human ARF4 Protein expressed in Escherichia coli (E. coli) - ABIN666652 : Mazelova, Astuto-Gribble, Inoue, Tam, Schonteich, Prekeris, Moritz, Randazzo, Deretic: Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4. in The EMBO journal 2009 (PubMed)
    Show all 2 references for ABIN666652

  2. Human ARF4 Protein expressed in Wheat germ - ABIN1345461 : Norton, Lawson, Mahdi, Freytag, Clements: The A subunit of Escherichia coli heat-labile enterotoxin functions as a mucosal adjuvant and promotes IgG2a, IgA, and Th17 responses to vaccine antigens. in Infection and immunity 2012 (PubMed)

More Proteins for ADP-Ribosylation Factor 4 Interaction Partners

Xenopus laevis ADP-Ribosylation Factor 4 (ARF4) interaction partners

  1. The newly identified ciliary targeting VxPx motif present in rhodopsin binds the small GTPase (show RACGAP1 Proteins) Arf4 and regulates its association with the trans-Golgi network.

Mouse (Murine) ADP-Ribosylation Factor 4 (ARF4) interaction partners

  1. ARF4 is required for Presenilin basal body localization, Notch (show NOTCH1 Proteins) signaling, and subsequent epidermal differentiation.

  2. These findings are consistent with Arf4 playing a critical role in endomembrane trafficking, particularly in the pancreas, but not in ciliary function.

  3. This work suggests that while Arf4 is not required for ciliary assembly, it is important for the efficient transport of fibrocystin to cilia, and also plays critical roles in non-ciliary processes

  4. Findings suggest that Arf4 is a critical modulator of DG-mediated pattern separation by regulating dendritic spine development.

  5. ASAP1 is a scaffold bringing together the proteins needed for transport to the cilia including the GTP-binding protein Arf4 & the 2 G proteins of the Rab family--Rab11 & Rab8--linked by the Rab8 guanine nucleotide exchange factor Rabin8.

  6. somal CAPS2 (show CADPS2 Proteins) is associated with the Golgi membrane, and mediates binding and recruitment of the GDP-bound form of ARF4 and ARF5 (show ARF5 Proteins) to the Golgi membrane

  7. a functional role for CAPS1 (show CAPS Proteins) in regulating DCV trafficking in the trans-Golgi network; this activity occurs via protein-protein interaction with ARF4/ARF5 (show ARF5 Proteins) in a GDP-dependent manner.

Human ADP-Ribosylation Factor 4 (ARF4) interaction partners

  1. ARF1 (show ARF1 Proteins)+ARF4 are required for integrity of recycling endosomes but are involved in distinct transport pathways: the pair regulates retrograde transport from endosomes to the TGN (show TG Proteins).

  2. A CREB3 (show CREB3 Proteins)-ARF4 signalling cascade may be part of a Golgi stress response set in motion by stimuli compromising Golgi capacity.

  3. a crucial role for class II Arf proteins (Arf4 and Arf5 (show ARF5 Proteins)) in the dengue flavivirus life cycle

  4. The lipid droplets deposition and the cellular triacylglycerol content are significantly increased by siRNA-mediated depletion of Arf4.

  5. sLZIP-regulated ARF4 expression in response to phorbol 12-myristate 13-acetate is involved in breast cancer cell migration.

  6. Arf4 regulates PLA2G6 (show PLA2G6 Proteins)-A activity together with Arf1 (show ARF1 Proteins); and gene silencing of Arf4 was shown to alter cytosolic coat protein (show GOLPH3 Proteins) I (show ANXA2 Proteins) subunit recruitment to the early secretory pathway.

  7. ARF4 is a critical molecule that directly regulates cellular phospholipase D2 (show PLD2 Proteins) activity and this ARF4-mediated PLD2 (show PLD2 Proteins) activation stimulates AP-1 (show FOSB Proteins)-dependent transcription in the EGF (show EGF Proteins)-induced cellular response

  8. ARF4L (show ARL4D Proteins) occurred on the plasma membrane after binding to GTP (show AK3 Proteins) and into endosomes while binding to GDP; the inactive form of ARF4L (show ARL4D Proteins) causes localization of transferrin (show Tf Proteins) receptors to the endosomes while the active form causes transport to the plasma membrane.

  9. ARF4 participates in the regulation of glioblastoma apoptosis through the inhibition of stress-mediated apoptotic signals

Pig (Porcine) ADP-Ribosylation Factor 4 (ARF4) interaction partners

  1. swine ARF4 gene is over expressed in muscle, fat, heart, spleen, liver, and ovary and moderately expressed in lung and kidney but weakly expressed in small intestine

ADP-Ribosylation Factor 4 (ARF4) Protein Profile

Protein Summary

This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III\; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene.

Alternative names and synonyms associated with ADP-Ribosylation Factor 4 (ARF4)

  • ADP ribosylation factor 4 (arf4)
  • ADP-ribosylation factor 2 (Arf2)
  • ADP-ribosylation factor 4 (ARF4)
  • ADP-ribosylation factor 4 (Arf4)
  • AA407803 protein
  • ARF2 protein

Protein level used designations for ARF4

ADP-ribosylation factor 4 , ADP-ribosylation factor 2 , ADP-ribosylation factor family-like protein

779066 Xenopus laevis
11841 Mus musculus
79119 Rattus norvegicus
378 Homo sapiens
11843 Mus musculus
79120 Rattus norvegicus
518601 Bos taurus
595108 Sus scrofa
282601 Bos taurus
100172194 Pongo abelii
100723892 Cavia porcellus
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