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suggest that the interplay between 14-3-3 (show YWHAQ Antibodies), SAM (show TTN Antibodies) domain and CABIT domain might be responsible for the distribution of GAREM1 in mammalian cells.
Data indicate that a subtype of GAREM, GAREM2, is specifically expressed in the mouse, rat, and human brain.
Extracellular signal-regulated kinase activation in response to epidermal growth factor (show EGF Antibodies) stimulation is regulated by the expression of GAREM in COS-7 and HeLa cells.
This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.
family with sequence similarity 59, member A
, GRB2-associated and regulator of MAPK protein
, GRB2-associated and regulator of MAPK1
, Grb2-associated and regulator of Erk/MAPK
, protein FAM59A