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Browse our phosphodiesterase 6G, CGMP-Specific, Rod, gamma Proteins (PDE6G)

Full name:
phosphodiesterase 6G, CGMP-Specific, Rod, gamma Proteins (PDE6G)
On www.antibodies-online.com are 4 phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G) Proteins from 3 different suppliers available. Additionally we are shipping phosphodiesterase 6G, CGMP-Specific, Rod, gamma Antibodies (19) and many more products for this protein. A total of 26 phosphodiesterase 6G, CGMP-Specific, Rod, gamma products are currently listed.
Synonyms:
p3AT, Pde6g, Pdeg, RP57
list all proteins Gene Name GeneID UniProt
PDE6G 5148 P18545
PDE6G 18588 P09174
PDE6G 114248 P61250

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More Proteins for phosphodiesterase 6G, CGMP-Specific, Rod, gamma Interaction Partners

Cow (Bovine) phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G) interaction partners

  1. Transducin (show GNAT1 Proteins) activation of PDE6 appears to require interaction with both the C terminus and other regions of Pgamma to effectively relieve its inhibitory constraint.

Human phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G) interaction partners

  1. Collectively, we report previously unrecognized PDE6 expression in human lungs, significant alterations of the PDE6D (show PDE6D Proteins) and PDE6G/H subunits in IPF lungs.

  2. These findings demonstrate the positive role of the gamma subunit in maintaining phosphodiesterase activity and confirm the contribution of PDE6G to the etiology of retinitis pigmentosa in humans.

  3. The C-terminus of PED gamma occludes the active site of PDE6, thereby preventing hydrolysis of cGMP.

  4. PDEG functions to link c-Src (show SRC Proteins) and G-protein-coupled receptor kinase 2 (show ADRBK1 Proteins) in a signaling unit that regulates p42/p44 (show PSMC6 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) by epidermal growth factor (show EGF Proteins)

  5. Crystal structures of a chimaeric PDE5 (show PDE5A Proteins)/PDE6 catalytic domain (PDE5 (show PDE5A Proteins)/6cd) complexed with sildenafil or 3-isobutyl-1-methylxanthine and the Pgamma-inhibitory peptide Pgamma(70-87) have been determined at 2.9 and 3.0 A, respectively.

Mouse (Murine) phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G) interaction partners

  1. The presence of rod PDE6G in cones indicating functional substitution of PDE6h (show PDE6H Proteins) in mice.

phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G) Protein Profile

Protein Summary

This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G)

  • phosphodiesterase 6G, cGMP-specific, rod, gamma (PDE6G)
  • phosphodiesterase 6G, cGMP-specific, rod, gamma (Pde6g)
  • phosphodiesterase 6H, cGMP-specific, cone, gamma (Pde6h)
  • p3AT protein
  • Pde6g protein
  • Pdeg protein
  • RP57 protein

Protein level used designations for PDE6G

phosphodiesterase 6 gamma subunit rod form , retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma , GMP-PDE gamma , phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide , rod cG-PDE G , cGMP phosphodiesterase gamma , rod cyclic-GMP phosphodiesterase 6 gamma splice variant p3 , cyclic-GMP phosphodiesterase gamma subunit , phosphodiesterase 6G, cGMP-specific, rod, gamma , retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

GENE ID SPECIES
395091 Gallus gallus
281977 Bos taurus
101117520 Ovis aries
5148 Homo sapiens
18588 Mus musculus
403911 Canis lupus familiaris
114248 Rattus norvegicus
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