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Phospholipase C, epsilon 1 ELISA Kits (PLCE1)
On www.antibodies-online.com are 0 Phospholipase C, epsilon 1 (PLCE1) ELISA Kits from different suppliers available. Additionally we are shipping PLCE1 Proteins (3) and and many more products for this protein. A total of 5 PLCE1 products are currently listed.
Synonyms:
4933403A21Rik, mKIAA1516, NPHS3, Plce, PLCE1, PLCepsilon, PPLC
list all ELISA KIts Gene Name GeneID UniProt
Human PLCE1 PLCE1 51196 Q9P212
Mouse PLCE1 PLCE1 74055 Q8K4S1
Rat PLCE1 PLCE1 114633 Q99P84

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More ELISA Kits for PLCE1 Interaction Partners

Zebrafish Phospholipase C, epsilon 1 (PLCE1) interaction partners

  1. Results suggest that zebrafish may be used as a model organism to address the function of PLCepsilon 1 during the development of organs.

Human Phospholipase C, epsilon 1 (PLCE1) interaction partners

  1. No association between PLCE1 genotype and early viremia level in dengue patients.

  2. PLCE1 single-nucleotide polymorphism is associated with migraine.

  3. PLCE1 expression was found in the invasive carcinoma but not in the carcinoma in situ samples. Snail (show SNAI1 ELISA Kits) expression in the human ESCC samples significantly correlated with the PLCE1 protein level, and expression of Snail (show SNAI1 ELISA Kits) target genes in human esophageal cancer samples were also correlated with the PLCE1 abundance.

  4. results have shown a novel role of PLCepsilon in the maintenance of endothelial barrier function, via its CDC25 GEF domain and lipase activity, and subsequent up-regulation of Rap1 activity

  5. High PLC (show HSPG2 ELISA Kits) epsilon expression is associated with breast cancer.

  6. The mRNA expressions of PPP3CB (show PPP3CB ELISA Kits) and MEF2C (show MEF2C ELISA Kits) were significantly up-regulated, and CAMK1 (show CAMK1 ELISA Kits) and PPP3R1 (show PPP3R1 ELISA Kits) were significantly down-regulated in mitral regurgitation(MR) patients compared to normal subjects. Moreover, MR patients had significantly increased mRNA levels of PPP3CB (show PPP3CB ELISA Kits), MEF2C (show MEF2C ELISA Kits) and PLCE1 compared to aortic valve disease patients

  7. Two novel putatively deleterious PLCE1 variants were identified in children with steroid-resistant nephrotic syndrome.

  8. PLC (show HSPG2 ELISA Kits)-epsilon is a novel regulator of endothelial cell inflammation and vascular endothelial permeability.

  9. Taken together, our data highlight the pivotal role of miR (show MLXIP ELISA Kits)-1976 in the progression of NSCLC. Thus, miR (show MLXIP ELISA Kits)-1976 may be a potential prognostic marker and of treatment relevance for NSCLC progression intervention.

  10. this study presents the impact of a single nucleotide transition at SNPs associated with DSS (show NR0B1 ELISA Kits) on differential protein binding patterns with PLCE1 and MICB (show MICB ELISA Kits) genes and on protein structure modification and their possible role in the pathogenesis of dengue shock syndrome

Mouse (Murine) Phospholipase C, epsilon 1 (PLCE1) interaction partners

  1. 2-arachidonoylglycerol (2-AG) is an endogenous cannabinoid that depresses synaptic transmission through stimulation of CB1 (show CNR1 ELISA Kits) receptors. Among the six isoforms of phospholipase C (PLC (show PLC ELISA Kits); PLCbeta, PLCgamma, PLCdelta, PLCepsilon, PLCzeta (show PLCz1 ELISA Kits), PLCeta), only PLCbeta has been linked to 2-AG synthesis. Here we demonstrate that 8-CPT (show DHDDS ELISA Kits)-2Me-cAMP, a selective agonist of the cAMP sensor protein Epac (show RAPGEF3 ELISA Kits), enhances 2-AG-mediated synaptic depress...

  2. study shed light on a novel role of PLCepsilon in wound healing and provided new therapeutic approaches to target PLCepsilon for diminishing scar formation after injury

  3. PLCepsilon is crucial for N-butyl-N-(4-hydroxybutyl) nitrosamine induced bladder carcinogenesis.

  4. Thrombin (show F2 ELISA Kits) promotes sustained signaling and inflammatory gene expression through the CDC25 (show CDC25C ELISA Kits) and Ras-associating domains of phospholipase C epsilon.

  5. PLCepsilon plays an important role in the pathogenesis of bronchial asthma through upregulating inflammatory cytokine production by the bronchial epithelial cells.

  6. a new pathway for TRPC6 (show TRPC6 ELISA Kits) activation by Phospholipase C epsilon

  7. findings reveal a pathway initiated by GPCR (show GPBAR1 ELISA Kits) agonist-induced RhoA (show RHOA ELISA Kits) activation, in which PLCepsilon signals to PKD1 (show PKD1 ELISA Kits)-mediated phosphorylation of cytoskeletal proteins

  8. Activity of PLCepsilon contributes to chemotaxis of fibroblasts towards PDGF (show PDGFA ELISA Kits).

  9. PLCepsilon links G protein-coupled receptors (GPCR (show GPBAR1 ELISA Kits)) to sustained PKD (show PRKD1 ELISA Kits) activation, providing a means for GPCR (show GPBAR1 ELISA Kits) ligands that couple to RhoA (show RHOA ELISA Kits) to induce NF-kappaB (show NFKB1 ELISA Kits) signaling and promote neuroinflammation.

  10. These results reveal a crucial role of PLCepsilon in the development of skin inflammation and suggest a mechanism in which PLCepsilon induces the production of cytokines including IL-23 (show IL23A ELISA Kits) from keratinocytes, leading to the activation of IL-22 (show IL22 ELISA Kits)-producing T cells.

PLCE1 Antigen Profile

Antigen Summary

This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). These second messengers subsequently regulate various processes affecting cell growth, differentiation, and gene expression. This enzyme is regulated by small monomeric GTPases of the Ras and Rho families and by heterotrimeric G proteins. In addition to its phospholipase C catalytic activity, this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity. Mutations in this gene cause early-onset nephrotic syndrome\; characterized by proteinuria, edema, and diffuse mesangial sclerosis or focal and segmental glomerulosclerosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with PLCE1

  • phospholipase C, epsilon 1 (PLCE1) Elisa Kit
  • phospholipase C, epsilon 1 (plce1) Elisa Kit
  • phospholipase C, epsilon 1 (LOC100344504) Elisa Kit
  • phospholipase C, epsilon 1 (Plce1) Elisa Kit
  • 4933403A21Rik Elisa Kit
  • mKIAA1516 Elisa Kit
  • NPHS3 Elisa Kit
  • Plce Elisa Kit
  • PLCE1 Elisa Kit
  • PLCepsilon Elisa Kit
  • PPLC Elisa Kit

Protein level used designations for PLCE1

phospholipase C, epsilon 1 , pancreas-enriched phospholipase C , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1-like , 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 , PLC-epsilon-1 , phosphoinositide phospholipase C-epsilon-1 , phosphoinositide-specific phospholipase C epsilon-1 , phospholipase C-epsilon-1 , phospholipase C epsilon

GENE ID SPECIES
428962 Gallus gallus
450620 Pan troglodytes
486808 Canis lupus familiaris
519037 Bos taurus
568288 Danio rerio
701758 Macaca mulatta
100023487 Monodelphis domestica
100061676 Equus caballus
100152908 Sus scrofa
100344504 Oryctolagus cuniculus
100385383 Callithrix jacchus
100444145 Pongo abelii
100479318 Ailuropoda melanoleuca
100495530 Xenopus (Silurana) tropicalis
100540174 Meleagris gallopavo
100552081 Anolis carolinensis
100599747 Nomascus leucogenys
51196 Homo sapiens
74055 Mus musculus
114633 Rattus norvegicus
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