Browse our anti-PTK2B (PTK2B) Antibodies

Full name:
anti-PTK2B Protein tyrosine Kinase 2 beta Antibodies (PTK2B)
On www.antibodies-online.com are 257 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Antibodies from 26 different suppliers available. Additionally we are shipping PTK2B Kits (21) and PTK2B Proteins (14) and many more products for this protein. A total of 310 PTK2B products are currently listed.
Synonyms:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk
list all antibodies Gene Name GeneID UniProt
PTK2B 24185 P47196
PTK2B 11651 P31750
PTK2B 2185 Q14289

Show all species

Show all synonyms

All available anti-PTK2B Antibodies

Go to our pre-filtered search.

Top referenced anti-PTK2B Antibodies

  1. Human Polyclonal PTK2B Primary Antibody for IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. in The Journal of clinical investigation 2004 (PubMed)
    Show all 5 references for 196952

  2. Human Monoclonal PTK2B Primary Antibody for IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. in Experimental hematology 2004 (PubMed)
    Show all 3 references for 1724705

  3. Human Polyclonal PTK2B Primary Antibody for ELISA, WB - ABIN1533144 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. in Nature 1995 (PubMed)
    Show all 2 references for 1533144

  4. Human Polyclonal PTK2B Primary Antibody for IHC, ELISA - ABIN1532112 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. in Genomics 1997 (PubMed)
    Show all 2 references for 1532112

  5. Human Polyclonal PTK2B Primary Antibody for IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for 197440

  6. Human Polyclonal PTK2B Primary Antibody for IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. in Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody for WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. in American journal of physiology. Cell physiology 2004 (PubMed)

  8. Human Polyclonal PTK2B Primary Antibody for ICC, IF - ABIN257536 : Lu, Chen, Shimoda, Park, Zhang, Tran, Zhang, Semenza: Chemotherapy-Induced Ca(2+) Release Stimulates Breast Cancer Stem Cell Enrichment. in Cell reports 2017 (PubMed)

More Antibodies against PTK2B Interaction Partners

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex upregulation of OPN (show SPP1 Antibodies) expression is mediated by transcription factor SOX9 (show SOX9 Antibodies) in an mTOR (show FRAP1 Antibodies)-independent manner. Moreover, ablation of OPN (show SPP1 Antibodies) by deficient TSC1 (show TSC1 Antibodies)/TSC2 (show TSC2 Antibodies) complex contributed to inactivation of AKT (show AKT1 Antibodies) in TSC (show SLC12A3 Antibodies) cells

  2. Our results suggest that increasing Akt (show AKT1 Antibodies)/ NF-kappaB (show NFKB1 Antibodies) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (show PTEN Antibodies)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (show PTEN Antibodies) is a key regulatory player in the PI3K/PTEN (show PTEN Antibodies)/AKT (show AKT1 Antibodies) pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt (show AKT1 Antibodies) activation that tracks both the biochemical state and the physical location of Akt (show AKT1 Antibodies), is reported.

  6. Psgl-1 (show SELPLG Antibodies) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT (show AKT1 Antibodies) axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (show HSP90 Antibodies) and the PI3K/AKT (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) pathway in prostate cancer.

  8. results show that Pyk2 contributes to cytotoxic T lymphocyte(CTL) migration by regulating detachment of CTL at the trailing edge, which could explain why Pyk2 is important for chemotactic and migratory responses.

  9. Furthermore, Leishmania RNA virus 1-induced TLR-3 (show TLR3 Antibodies) activation promoted parasite persistence by enhancing macrophage survival through Akt (show AKT1 Antibodies) activation in a manner partially dependent on miR (show MLXIP Antibodies)-155.

  10. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (show CCL2 Antibodies) proliferation, and was associated with inhibition of PI3K/Akt (show AKT1 Antibodies) signaling pathway through activation of GPR120 (show O3FAR1 Antibodies).

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Our findings suggest that Pyk2 plays an important role in the coordination of stabilization of beta-catenin (show CTNNB1 Antibodies) in the crosstalk between Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) and Wnt (show WNT2 Antibodies)/Ca(2 (show CA2 Antibodies)+) signaling pathways upon Wnt3a (show WNT3A Antibodies) stimulation in differentiating hNPCs.

  2. STIM1 (show STIM1 Antibodies)-induced Ca(2 (show CA2 Antibodies)+) signaling activates Pyk2 to inhibit the interaction of VE-PTP (show PTPRB Antibodies) and VE-cadherin (show CDH5 Antibodies) and hence increase endothelial permeability.

  3. Ascites and CCL18 (show CCL18 Antibodies) stimulate the phosphorylation and expression of Pyk2, which positively regulates ascites-induced ovarian cancer cell migration.

  4. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (show PIK3CA Antibodies)-Akt/PKB (show AKT1 Antibodies) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  5. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  6. Studies suggest that PYK2 is a common downstream effector of ErbB (show EGFR Antibodies) and IL8 (show IL8 Antibodies) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  7. Pyk2 is a key downstream signaling molecules of CCR7 (show CCR7 Antibodies) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  8. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  9. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (show LPXN Antibodies).

  10. Src (show SRC Antibodies) has a role in priming Pyk2 (but not FAK (show PTK2 Antibodies)) phosphorylation and subsequent activation downstream of integrins

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) antibody
  • thymoma viral proto-oncogene 1 (Akt1) antibody
  • protein tyrosine kinase 2 beta (PTK2B) antibody
  • protein tyrosine kinase 2 beta (Ptk2b) antibody
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) antibody
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) antibody
  • Akt antibody
  • CADTK antibody
  • CAKB antibody
  • CAKbeta antibody
  • E430023O05Rik antibody
  • FADK2 antibody
  • FAK2 antibody
  • PKB antibody
  • PKB/Akt antibody
  • PKBalpha antibody
  • PTK antibody
  • Pyk2 antibody
  • Rac antibody
  • Raftk antibody

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
Selected quality suppliers for anti-PTK2B (PTK2B) Antibodies
Did you look for something else?