Browse our anti-PTPN2 (PTPN2) Antibodies

Full name:
anti-Protein tyrosine Phosphatase, Non-Receptor Type 2 Antibodies (PTPN2)
On www.antibodies-online.com are 69 Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) Antibodies from 18 different suppliers available. Additionally we are shipping PTPN2 Proteins (11) and PTPN2 Kits (2) and many more products for this protein. A total of 97 PTPN2 products are currently listed.
Synonyms:
AI325124, cb806, PTN2, PTP-1B, ptpn2, ptpn2l, Ptpt, TC-PTP, TCELLPTP, TCPTP, wu:fc10h07, zgc:55339, zgc:76973
list all antibodies Gene Name GeneID UniProt
PTPN2 5771 P17706
PTPN2 19255 Q06180
PTPN2 117063 P35233

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anti-Human PTPN2 Antibodies:

anti-Mouse (Murine) PTPN2 Antibodies:

anti-Rat (Rattus) PTPN2 Antibodies:

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Top referenced anti-PTPN2 Antibodies

  1. Cow (Bovine) Polyclonal PTPN2 Primary Antibody for WB - ABIN2782194 : Shimizu, Miyakawa, Iwata, Kuribara, Tiganis, Morimoto, Ikeda, Kizaki: A novel mechanism for imatinib mesylate (STI571) resistance in CML cell line KT-1: role of TC-PTP in modulating signals downstream from the BCR-ABL fusion protein. in Experimental hematology 2004 (PubMed)

  2. Human Polyclonal PTPN2 Primary Antibody for IHC (p), WB - ABIN657234 : Aradi, Kato, Filkova, Karouzakis, Klein, Scharl, Kolling, Michel, Gay, Buzas, Gay, Jüngel: Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2), an Important Regulator of IL-6 Production in Rheumatoid Arthritis Synovial Fibroblasts. in Arthritis & rheumatology (Hoboken, N.J.) 2015 (PubMed)

More Antibodies against PTPN2 Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) interaction partners

  1. PASD1 (show PASD1 Antibodies) serves as a critical nuclear positive regulator of STAT3 (show STAT3 Antibodies)-mediated gene expression and tumorigenesis.

  2. reported that SNPs in STAT4 (show STAT4 Antibodies), PTPN2, PSORS1C1 (show PSORS1C1 Antibodies), and TRAF3IP2 (show TRAF3IP2 Antibodies) are associated with response to TNF (show TNF Antibodies)-i treatment in RA patients; however, these findings should be validated in a larger population

  3. The results suggest that miR (show MLXIP Antibodies)-448 might promote Th17 differentiation in multiple sclerosis and thus aggravate the disease through inhibiting PTPN2.

  4. ACPA (show PRTN3 Antibodies) were associated significantly with rs7574865 in STAT-4 (show STAT4 Antibodies). The SNP rs2233945 in the PSORS1C1 (show PSORS1C1 Antibodies) gene was protective regarding the presence of bone erosions, while rs2542151 in PTPN2 gene was associated with joint damage.

  5. Inflammatory bowel disease patients carrying the C-allele of PTPN2 SNP rs1893217 are at greater risk for developing a severe disease course but are more likely to respond to treatment with anti-TNF (show TNF Antibodies) antibodies.

  6. The increase in miR (show MLXIP Antibodies)-210 resulted in down regulation of its target PTPN2 mRNA in pre-eclampsia.

  7. role of PTPN2 in type 1 diabetes and Crohn's disease (review)

  8. rs2542151 SNP in The PTPN2 gene is associated with T1DM in Chinese Han children

  9. Loss of protein tyrosine phosphatase (show ACP1 Antibodies), non-receptor type 2 is associated with activation of AKT (show AKT1 Antibodies) and tamoxifen resistance in breast cancer.

  10. Angiopoietin-1 (show ANGPT1 Antibodies) Regulates Brain Endothelial Permeability through PTPN-2 Mediated Tyrosine Dephosphorylation of Occludin (show OCLN Antibodies)

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2) interaction partners

  1. PTPN2 is a positive regulator of lipopolysaccharide-induced inflammatory response by enhancing the activity of Src (show SRC Antibodies) through targeting the inhibitory phosphor-tyrosine527 of Src (show SRC Antibodies).

  2. Loss of PTPN2 in intestinal epithelial cells has no significant influence on inflammation in dextran sulphate sodium-induced colitis. On the other hand, loss of PTPN2 induced enhanced epithelial cell proliferation and promoted wound closure.

  3. Antigen receptor-mediated depletion of FOXP3 (show FOXP3 Antibodies) in induced regulatory T-lymphocytes via PTPN2 and FOXO1 (show FOXO1 Antibodies)

  4. A novel role for TCPTP in insulin (show INS Antibodies) secretion and uncover STAT3 (show STAT3 Antibodies) as a physiologically relevant target for TCPTP in the endocrine pancreas.

  5. dysfunction of PTPN2 results in aberrant T-cell differentiation and intestinal dysbiosis similar to those observed in human CD. Our findings indicate a novel and crucial role for PTPN2 in chronic intestinal inflammation.

  6. PTPN2 attenuates T-cell lymphopenia-induced proliferation.

  7. demonstrate that SIPAR directly interacts with T cell protein tyrosine phosphatase TC45 and enhances its association with STAT3 (show STAT3 Antibodies)

  8. findings reveal a mechanism by which PTPN2 SNPs might convert a tolerogenic CD8 (show CD8A Antibodies)(+) T cell response into one capable of causing the destruction of pancreatic beta-cells.

  9. TC-PTP inhibits STAT3 (show STAT3 Antibodies)-mediated mouse keratinocyte skin cell proliferation and survival following UVB irradiation.

  10. Data suggest that spermidine supplementation and subsequent protein tyrosine phosphatase non-receptor type 2 (PTPN2) activation may be helpful in the treatment of chronic intestinal inflammation.

PTPN2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.

Alternative names and synonyms associated with PTPN2

  • protein tyrosine phosphatase, non-receptor type 2 (ptpn2) antibody
  • protein tyrosine phosphatase, non-receptor type 2 (PTPN2) antibody
  • protein tyrosine phosphatase, non-receptor type 2 (Ptpn2) antibody
  • protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b) antibody
  • AI325124 antibody
  • cb806 antibody
  • PTN2 antibody
  • PTP-1B antibody
  • ptpn2 antibody
  • ptpn2l antibody
  • Ptpt antibody
  • TC-PTP antibody
  • TCELLPTP antibody
  • TCPTP antibody
  • wu:fc10h07 antibody
  • zgc:55339 antibody
  • zgc:76973 antibody

Protein level used designations for PTPN2

T-cell protein tyrosine phosphatase , tyrosine-protein phosphatase non-receptor type 2 , MPTP , T cell protein-tyrosine phosphatase , protein-tyrosine phosphatase PTP-2 , protein-tyrosine phosphatase PTP-S , phosphoprotein phosphatase , protein tyrosine phosphatase 1B , protein tyrosine phosphatase, non-receptor type 2, like

GENE ID SPECIES
446745 Xenopus laevis
5771 Homo sapiens
490563 Canis lupus familiaris
540888 Bos taurus
19255 Mus musculus
117063 Rattus norvegicus
396409 Gallus gallus
561613 Danio rerio
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