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MDM2 antibody (Ser166)

Name: MDM2 antibody (Ser166)
SKU: ABIN540533
Price: 644.29 USD
Availability: InStock

MDM2 Reactivity: Human, Mouse, Rat IF, IHC (p) Host: Rabbit Polyclonal unconjugated

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MDM2 polyclonal antibody .

IHC

Immunofluorescence staining of methanol-fixed HeLa cells using MDM2 polyclonal antibody (Cat # PAB12253, Red).

2 images

(2 references)

Catalog No. ABIN540533

Datasheet as PDF

Target See all MDM2 Antibodies

MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
Binding Specificity
26

25

14

11

10

10

10

9

8

8

8

4

4

4

4

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Ser166
Reactivity
194

79

54

11

2

1

1

1

1

1
Human, Mouse, Rat
Host
169

28

1
Rabbit
Compatible Secondaries
Clonality
169

29
Polyclonal
Conjugate
99

13

9

9

7

6

6

6

6

6

6

6

2

2

2

2

2

2

2

1

1

1

1

1
This MDM2 antibody is un-conjugated
Application
126

77

64

37

28

27

27

18

18

14

10

10

5

4

3

2

2

1

1

1

1

1
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose

Rabbit polyclonal antibody raised against synthetic peptide of MDM2.

Sequence

AISET

Specificity

MDM2 (Ab-166) Antibody detects endogenous levels of total MDM2 protein.

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Antibody Reactive Against Synthetic Peptide.

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S166 of human MDM2.

Top Product

Discover our top product MDM2 Primary Antibody
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibody
MDM2 Reactivity: Human, Mouse WB, IF, IHC (p), IP, ICC, ChIP Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 101-200) antibody
MDM2 Reactivity: Human WB, ELISA, IHC (p), RNAi, PLA Host: Mouse Monoclonal 1A7 unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer166) antibody
MDM2 Reactivity: Human, Mouse, Monkey WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibody
MDM2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB7981 unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 26-169) antibody
MDM2 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 3C1E3 unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424) antibody
MDM2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) antibody
MDM2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer186) antibody
MDM2 Reactivity: Human WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) antibody
MDM2 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, IF, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 26-169) antibody
MDM2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 4A8D12 unconjugated

Application Notes

Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Mayo, Donner: "A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11598-603, (2001) (PubMed).

Zhou, Liao, Xia, Zou, Spohn, Hung: "HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation." in: Nature cell biology, Vol. 3, Issue 11, pp. 973-82, (2001) (PubMed).
Target

MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Alternative Name

MDM2 (MDM2 Products)

Synonyms

ACTFS antibody, HDMX antibody, hdm2 antibody, zgc:109834 antibody, 1700007J15Rik antibody, AA415488 antibody, Mdm-2 antibody, MDM2 proto-oncogene antibody, MDM2 proto-oncogene S homeolog antibody, Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse) antibody, MDM2 oncogene, E3 ubiquitin protein ligase antibody, transformed mouse 3T3 cell double minute 2 antibody, MDM2 antibody, mdm2.S antibody, Mdm2 antibody, mdm2 antibody

Gene ID

4193

Pathways

p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway