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BCL6 antibody (C-Term)
BCL6
Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-BCL6 Antibody
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Target
See all BCL6 Antibodies
BCL6
(B-Cell CLL/lymphoma 6 (BCL6))
Binding Specificity
All epitopes for BCL6 antibodies
C-Term
Reactivity
Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
Host
All hosts for BCL6 antibodies
Rabbit
Clonality
All clonalities for BCL6 antibodies
Polyclonal
Conjugate
All conjugates for BCL6 antibodies
This BCL6 antibody is un-conjugated
Application
All applications for BCL6 antibodies
Western Blotting (WB)
Sequence
IHTGEKPYHC EKCNLHFRHK SQLRLHLRQK HGAITNTKVQ YRVSATDLPP
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
Characteristics
This is a rabbit polyclonal antibody against BCL6. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human BCL6
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Application Details
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Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for BCL6
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Target
BCL6
(B-Cell CLL/lymphoma 6 (BCL6))
Alternative Name
BCL6 (BCL6 Products )
Synonyms
bcl5 antibody, laz3 antibody, bcl6a antibody, znf51 antibody, zbtb27 antibody, MGC132260 antibody, Bcl5 antibody, BCL5 antibody, BCL6A antibody, LAZ3 antibody, ZBTB27 antibody, ZNF51 antibody, B-cell CLL/lymphoma 6 L homeolog antibody, B-cell CLL/lymphoma 6 antibody, B cell leukemia/lymphoma 6 antibody, bcl6.L antibody, bcl6 antibody, BCL6 antibody, Bcl6 antibody
Background
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. Alias Symbols: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27 Protein Size: 706
Molecular Weight
77 kDa
Gene ID
604
NCBI Accession
NM_001130845 , NP_001124317
UniProt
P41182
Pathways
Chromatin Binding , Regulation of Leukocyte Mediated Immunity , Production of Molecular Mediator of Immune Response , Protein targeting to Nucleus
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