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FOSB antibody (C-Term)

FOSB Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042399
  • Target See all FOSB Antibodies
    FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
    Binding Specificity
    • 19
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 264-291, C-Term
    Reactivity
    • 65
    • 29
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 59
    • 6
    Rabbit
    Clonality
    • 51
    • 14
    Polyclonal
    Conjugate
    • 32
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOSB antibody is un-conjugated
    Application
    • 45
    • 15
    • 15
    • 11
    • 11
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Protein fosB(FOSB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    LPFQTSQDAP PNLTASLFTH SEVQVLGD
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Protein fosB(FOSB) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: FBJ murine osteosarcoma viral oncogene homolog B
    Protein Name: Protein fosB
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Fos B (264-291aa LPFQTSQDAPPNLTASLFTHSEVQVLGD), different from the related mouse sequence by two amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product FOSB Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
    Alternative Name
    FOSB (FOSB Products)
    Synonyms
    FOSB antibody, zgc:92354 antibody, AP-1 antibody, G0S3 antibody, GOS3 antibody, GOSB antibody, fra-2 antibody, FBJ murine osteosarcoma viral oncogene homolog B antibody, FosB proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene B antibody, FOSB antibody, fosb antibody, Fosb antibody
    Background
    FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

    Synonyms: DKFZp686C0818 antibody|FBJ murine osteosarcoma viral oncogene homolog B antibody|fosB antibody|FOSB_HUMAN antibody|G0/G1 switch regulatory protein 3 antibody|G0S3 antibody|GOS 3 antibody|GOS B antibody|GOS3 antibody|GOSB antibody|MGC42291 antibody|Oncogene FOS B antibody|Oncogene FOSB antibody|Protein fos B antibody|Protein fosB antibody
    Gene ID
    2354
    UniProt
    P53539
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