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G3BP1 antibody (N-Term)

G3BP1 Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780221
  • Target See all G3BP1 Antibodies
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Binding Specificity
    • 21
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 73
    • 25
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Rabbit, Pig
    Host
    • 69
    • 3
    • 1
    Rabbit
    Clonality
    • 69
    • 4
    Polyclonal
    Conjugate
    • 42
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This G3BP1 antibody is un-conjugated
    Application
    • 66
    • 32
    • 29
    • 16
    • 13
    • 13
    • 11
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EVFGGFVTEP QEESEEEVEE PEERQQTPEV VPDDSGTFYD QAVVSNDMEE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against G3BP. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human G3BP
    Top Product
    Discover our top product G3BP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 466 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lind, Svedin, Domsgen, Kapell, Laitinen, Moll, Flodström-Tullberg: "Coxsackievirus counters the host innate immune response by blocking type III interferon expression." in: The Journal of general virology, Vol. 97, Issue 6, pp. 1-12, (2016) (PubMed).

    Schulte, Liu, Panas, Thaa, Dickson, Götte, Achour, McInerney: "Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication." in: Open biology, Vol. 6, Issue 7, (2016) (PubMed).

  • Target
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Alternative Name
    G3BP (G3BP1 Products)
    Synonyms
    G3BP antibody, HDH-VIII antibody, fj17h05 antibody, zgc:56034 antibody, wu:fj17h05 antibody, g3bp antibody, MGC53271 antibody, G3BP1 antibody, G3bp antibody, RGD1310666 antibody, AI849976 antibody, B430204O07 antibody, C87777 antibody, mKIAA4115 antibody, G3BP stress granule assembly factor 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 L homeolog antibody, Ras-GTPase-activating protein SH3-domain-binding protein antibody, G3BP1 antibody, g3bp1 antibody, g3bp1.L antibody, LOC100304885 antibody, G3bp1 antibody
    Background
    G3BP is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
    Alias Symbols: G3BP, HDH-VIII
    Protein Interaction Partner: UBC, USP10, FXR2, MDM2, RNF2, BMI1, RPS27L, EDC4, RPL35, RPL14, EIF2B3, EIF3C, PTBP1, PIN1, PA2G4, YBX1, HNRNPU, FAU, SH3RF2, TARDBP, FBXO25, RIOK2, SND1, VCAM1, env, ITGA4, IL7R, FN1, EPHA8, DTX1, PABPC1, PAXIP1, ESR1, APP, NOLC1, TPM4, LCK, CSK, KCND3,
    Protein Size: 466
    Molecular Weight
    51 kDa
    Gene ID
    10146
    NCBI Accession
    NM_005754, NP_005745
    UniProt
    Q13283
    Pathways
    SARS-CoV-2 Protein Interactome
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