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p53 antibody (AA 14-389) (FITC)

TP53 Reactivity: Human, Mouse, Rat, Monkey, Cow, Dog, Chicken, Chinese Hamster, Golden Syrian Hamster IF, FACS, ICC Host: Mouse Monoclonal PAb240 FITC

Catalog No. ABIN4880089

Datasheet as PDF

Target See all p53 (TP53) Antibodies

p53 (TP53) (Tumor Protein P53 (TP53))
Binding Specificity
51

41

40

39

32

30

28

25

24

24

23

20

20

20

18

18

16

16

14

13

10

9

9

9

9

9

7

7

7

7

7

7

6

6

6

6

5

5

5

4

4

4

3

3

3

3

3

3

3

3
AA 14-389
Reactivity
888

268

219

109

44

33

31

17

10

8

8

6

4

4

3

2

2

2

1

1

1

1

1

1

1
Human, Mouse, Rat, Monkey, Cow, Dog, Chicken, Chinese Hamster, Golden Syrian Hamster
Host
676

227

6

2

1

1
Mouse
Compatible Secondaries
Clonality
611

301

1
Monoclonal
Conjugate
509

49

38

26

25

24

24

24

22

22

22

13

13

13

13

13

13

5

5

5

5

5

5

2

2

2

2

2

2

2

1

1

1

1

1

1
This p53 antibody is conjugated to FITC
Application
718

336

253

216

207

150

124

123

119

62

60

32

20

17

13

12

12

10

9

8

6

4

3

2

2

2

1

1

1

1

1
Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Specificity

This antibody recognises cellular tumour antigen p53, a 50 kDa transcription factor and major tumour suppressor that plays a major role in regulating cellular responses to DNA damage and other genomic aberrations. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. The Pab240 antibody recognizes an epitope between amino acids 156-214 on murine p53.

Purification

Purified on protein A from tissue culture supernatant.

Immunogen

Purified p53-b-galactosidase fusion protein containing p53 sequence from amino acids 14-389

Clone

PAb240

Isotype

IgG1

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TP53 Reactivity: Human WB, IHC, IP Host: Rabbit Polyclonal unconjugated

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TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

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TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

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TP53 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, IP, ICC Host: Rabbit Polyclonal unconjugated

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TP53 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB7777 unconjugated

anti-Tumor Protein P53 (TP53) (pSer33) antibody
TP53 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal antibody dilution should be determined by titration

Comment

Myeloma, fusion partners: Cells from immunized Balb/c mice were fused with the Sp2/0-Ag.14 myeloma cell line

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link®, supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name

P53 (TP53 Products)

Synonyms

BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody

OMIM

191170

Pathways

p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect