FDFT1 antibody (N-Term)
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- Target See all FDFT1 Antibodies
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FDFT1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- HSFLYQPDWR FMESKEKDRQ VLEDFPTISL EFRNLAEKYQ TVIADICRRM
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against FDFT1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FDFT1
- Top Product
- Discover our top product FDFT1 Primary Antibody
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anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 269-417) antibody
FDFT1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 Reactivity: Human, Monkey WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 2F10 unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 140-170) antibodyFDFT1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB4781-4782 unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-260) antibodyFDFT1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 10-148) antibodyFDFT1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 2-417) antibodyFDFT1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Monoclonal 10H12 unconjugated Recombinant Antibody
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (AA 1-30), (N-Term) antibodyFDFT1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB04780 unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) (N-Term) antibodyFDFT1 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1) antibodyFDFT1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 417 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
- Alternative Name
- FDFT1 (FDFT1 Products)
- Synonyms
- FDFT1 antibody, DKFZp459C1712 antibody, SQS antibody, SS antibody, DGPT antibody, ERG9 antibody, fdft1 antibody, farnesyl-diphosphate farnesyltransferase 1 antibody, squalene synthase antibody, farnesyl diphosphate farnesyl transferase 1 antibody, FDFT1 antibody, fdft1 antibody, LOC100560926 antibody, Fdft1 antibody
- Background
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FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DGPT, ERG9, SQS, SS
Protein Interaction Partner: UBC, MDM2, FBXO6, EGFR, GLP1R, HDAC10, UBL4A, FN1, UBD, RUVBL2, TMEM43, FAM101A, SHPRH, ARL6IP1, ANXA5, SMNDC1, PSTPIP1, RUVBL1,
Protein Size: 417 - Molecular Weight
- 48 kDa
- Gene ID
- 2222
- NCBI Accession
- NM_004462, NP_004453
- UniProt
- P37268
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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