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FBXW5 antibody (N-Term)

FBXW5 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5516989
  • Target See all FBXW5 Antibodies
    FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
    Binding Specificity
    • 7
    • 5
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXW5 antibody is un-conjugated
    Application
    • 29
    • 13
    • 11
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    NDLTISLLHS ADMRPYNWSY TQFSQFNKDD SLLLASGVFL GPHNSSSGEI
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against FBXW5. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXW5
    Top Product
    Discover our top product FBXW5 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
    Alternative Name
    FBXW5 (FBXW5 Products)
    Synonyms
    Fbw5 antibody, AI159739 antibody, F-box and WD repeat domain containing 5 antibody, F-box and WD-40 domain protein 5 antibody, FBXW5 antibody, Fbxw5 antibody
    Background
    This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

    Alias Symbols: FBXW5, FBW5, PP3971,

    Protein Interaction Partner: KRT40, KRTAP9-4, ADAMTSL4, CUL1, UBC, TRIM27, KRT31, NOTCH2NL, KRTAP10-3, KRTAP10-8, CUL3, SKP1, TNFAIP8L1, TSC2, DLC1, HSP90AA1, NEDD8, MAP3K7, CUL4A, REST, MYB, DDB1, UBE2R2, SASS6, PLK4, CDC20, WDR20, KRTAP4-12, MDFI, TSC1, NLK,

    Protein Size: 566
    Gene ID
    54461
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