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AFT1 antibody (C-Term)

AFT1 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Sheep WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780654
  • Target See all AFT1 Antibodies
    AFT1 (Activating Transcription Factor 1 (AFT1))
    Binding Specificity
    • 28
    • 13
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 109
    • 45
    • 24
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Sheep
    Host
    • 102
    • 7
    • 2
    • 1
    Rabbit
    Clonality
    • 98
    • 14
    Polyclonal
    Conjugate
    • 59
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFT1 antibody is un-conjugated
    Application
    • 80
    • 37
    • 21
    • 15
    • 15
    • 14
    • 14
    • 11
    • 11
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKT LKDLYSNKSV
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ATF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ATF1
    Top Product
    Discover our top product AFT1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 271 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    AFT1 (Activating Transcription Factor 1 (AFT1))
    Alternative Name
    ATF1 (AFT1 Products)
    Synonyms
    ews-atf1 antibody, fus/atf-1 antibody, treb36 antibody, ATF1 antibody, EWS-ATF1 antibody, FUS/ATF-1 antibody, TREB36 antibody, Atf-1 antibody, wu:fc92c07 antibody, zgc:64099 antibody, activating transcription factor 1 antibody, activating transcription factor 1 L homeolog antibody, atf1 antibody, ATF1 antibody, MGC85066 antibody, atf1.L antibody, Atf1 antibody
    Background
    ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT [AC] [AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.
    Alias Symbols: EWS-ATF1, FUS/ATF-1, TREB36
    Protein Interaction Partner: UBC, SRA1, FOSL2, GABPB1, GABPA, EDF1, HNF1B, RPS6KA5, CAMK1, RPS6KA4, CAMK2G, PRKACA, CREBBP, SPI1, JUN, CREM, CREB1, ATF1, CSNK2A2, CSNK2A1, BRCA1, CSNK2B, CAMK2A, FOSL1,
    Protein Size: 271
    Molecular Weight
    29 kDa
    Gene ID
    466
    NCBI Accession
    NM_005171, NP_005162
    UniProt
    P18846
    Pathways
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
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