NAMPT antibody
(7 references)-
- Target See all NAMPT Antibodies
- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
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Reactivity
- Human, Rat, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NAMPT antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Specificity
- Recognizes human, mouse and rat Nampt.
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Sterility
- 0.2 μm filtered
- Immunogen
- Recombinant human Nampt (visfatin/PBEF).
- Clone
- OMNI379
- Isotype
- IgG2a
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anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-491) antibody
NAMPT Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) antibody (Biotin)NAMPT Reactivity: Human, Rat, Mouse WB, ELISA, IHC, ICC Host: Mouse Monoclonal OMNI379 Biotin
anti-Nicotinamide phosphoribosyltransferase (NAMPT) antibodyNAMPT Reactivity: Human, Rat, Mouse WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-280) antibodyNAMPT Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 301-400) antibodyNAMPT Reactivity: Human, Rat, Mouse WB, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 400-426) antibodyNAMPT Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB22920 unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 400-426) antibodyNAMPT Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-491) antibodyNAMPT Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D1 unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-280) antibodyNAMPT Reactivity: Human ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Nicotinamide phosphoribosyltransferase (NAMPT) (C-Term) antibodyNAMPT Reactivity: Human, Rat, Mouse WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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: "Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia." in: Blood, Vol. 125, Issue 1, pp. 111-23, (2015) (PubMed).
: "SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice." in: Cell metabolism, Vol. 21, Issue 5, pp. 706-17, (2015) (PubMed).
: "Expression and regulation of nampt in human islets." in: PLoS ONE, Vol. 8, Issue 3, pp. e58767, (2013) (PubMed).
: "Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 376-81, (2010) (PubMed).
: "Molecular characteristics of serum visfatin and differential detection by immunoassays." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 12, pp. 4783-91, (2007) (PubMed).
: "Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme." in: Cell metabolism, Vol. 6, Issue 5, pp. 363-75, (2007) (PubMed).
: "Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1." in: FEBS letters, Vol. 580, Issue 17, pp. 4105-13, (2006) (PubMed).
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: "Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia." in: Blood, Vol. 125, Issue 1, pp. 111-23, (2015) (PubMed).
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- Target
- NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
- Alternative Name
- Nampt (Visfatin/PBEF) (NAMPT Products)
- Synonyms
- 1110035O14Rik antibody, PBEF antibody, PBEF1 antibody, VF antibody, VISFATIN antibody, AI314458 antibody, AI480535 antibody, NAmPRTase antibody, Pbef antibody, Pbef1 antibody, Visfatin antibody, visfatin antibody, pbef antibody, pbef1 antibody, nicotinamide phosphoribosyltransferase antibody, Nicotinamide phosphoribosyltransferase antibody, nicotinamide phosphoribosyltransferase S homeolog antibody, NAMPT antibody, Nampt antibody, nampt antibody, Smon_0680 antibody, Mrub_2845 antibody, Cseg_3704 antibody, BC1002_3997 antibody, Ftrac_2686 antibody, Varpa_5681 antibody, Celal_3900 antibody, Deima_0880 antibody, BC1001_3724 antibody, Celly_1696 antibody, Clole_1542 antibody, Tsp_05934 antibody, nampt.S antibody
- Background
- Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
- UniProt
- P43490
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