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G3BP1 antibody (AA 214-303)

G3BP1 Reactivity: Human WB, ELISA, IF, IHC (p), RNAi Host: Mouse Monoclonal 2F3 unconjugated
Catalog No. ABIN564390
  • Target See all G3BP1 Antibodies
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Binding Specificity
    • 21
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 214-303
    Reactivity
    • 72
    • 26
    • 15
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 69
    • 2
    • 1
    Mouse
    Clonality
    • 70
    • 2
    Monoclonal
    Conjugate
    • 41
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This G3BP1 antibody is un-conjugated
    Application
    • 65
    • 32
    • 28
    • 14
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant G3BP.
    Sequence
    KPEPVLEETA PEDAQKSSSP APADIAQTVQ EDLRTFSWAS VTSKNLPPSG AVPVTGIPPH VVKVPASQPR PESKPESQIP PQRPQRDQRV
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    G3BP (AAH06997, 214 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2F3
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: "Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum." in: Journal of neurochemistry, Vol. 139, Issue 3, pp. 349-368, (2016) (PubMed).

    Kaehler, Isensee, Hucho, Lehrach, Krobitsch: "5-Fluorouracil affects assembly of stress granules based on RNA incorporation." in: Nucleic acids research, Vol. 42, Issue 10, pp. 6436-47, (2014) (PubMed).

    Martin, Zekri, Metz, Maurice, Chebli, Vignes, Tazi: "Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons." in: Journal of neurochemistry, (2013) (PubMed).

    Norazit, Meedeniya, Nguyen, Mackay-Sim: "Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle." in: Brain research, Vol. 1360, pp. 119-29, (2010) (PubMed).

  • Target
    G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
    Alternative Name
    G3BP1 (G3BP1 Products)
    Background
    Full Gene Name: GTPase activating protein (SH3 domain) binding protein 1
    Synonyms: G3BP,HDH-VIII,MGC111040
    Gene ID
    10146
    Pathways
    SARS-CoV-2 Protein Interactome
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