CYP4V2 antibody (Internal Region)
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- Target See all CYP4V2 Antibodies
- CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP4V2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Cytochrome P450 4V2 Antibody detects endogenous levels of total Cytochrome P450 4V2.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Cytochrome P450 4V2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- CYP4V2 (Cytochrome P450, Family 4, Subfamily V, Polypeptide 2 (CYP4V2))
- Alternative Name
- CYP4V2 (CYP4V2 Products)
- Synonyms
- BCD antibody, CYP4AH1 antibody, CYP4V antibody, bcd antibody, cyp4ah1 antibody, MGC147146 antibody, cytochrome P450 family 4 subfamily V member 2 antibody, cytochrome P450 family 4 subfamily V member 2 S homeolog antibody, cytochrome P450, family 4, subfamily V, polypeptide 2 antibody, cytochrome P450, family 4, subfamily v, polypeptide 2 antibody, CYP4V2 antibody, cyp4v2.S antibody, cyp4v2 antibody
- Background
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Description: Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592).
Gene: CYP4V2
- Molecular Weight
- 61 kDa
- Gene ID
- 285440
- UniProt
- Q6ZWL3
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