For best experience we recommend to activate Javascript in your browser.

Mesothelin antibody (AA 273-407)

Name: Mesothelin antibody (AA 273-407)
Brand: antibodies-online
SKU: ABIN6939032
Price: 597.38 USD
Availability: InStock

MSLN Reactivity: Human IHC (f) Host: Mouse Monoclonal MSLN-2131 unconjugated

Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with Mesothelin Mouse Monoclonal Antibody (MSLN/2131).

IHC

SDS-PAGE Analysis Purified Mesothelin Mouse Monoclonal Antibody (MSLN/2131).

SDS

Analysis of Protein Array containing more than 19,000 full-length human proteins using Mesothelin Mouse Monoclonal Antibody (MSLN/2131).

PAr

Formalin-fixed, paraffin-embedded human Lung Mesothelioma stained with Mesothelin Mouse Monoclonal Antibody (MSLN/2131).

7 images

Catalog No. ABIN6939032

Datasheet as PDF

Target See all Mesothelin (MSLN) Antibodies

Mesothelin (MSLN)
Binding Specificity
16

9

6

5

5

5

5

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 273-407
Reactivity
89

24

5

2

2

2

1

1

1
Human
Host
76

24

4

1

1
Mouse
Compatible Secondaries
Clonality
74

30

2
Monoclonal
Conjugate
68

12

8

6

1

1

1

1

1

1

1

1

1

1

1

1
This Mesothelin antibody is un-conjugated
Application
68

51

24

22

12

11

9

4

4

4

2

2

2

2

1

1

1

1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity

Mesothelin is a 40 kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69 kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Cross-Reactivity (Details)

Human, Mouse, Rat,

Purification

200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen

Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)

Clone

MSLN-2131

Isotype

IgG2b
anti-Mesothelin (MSLN) (AA 101-200) antibody
MSLN Reactivity: Human ELISA, WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Mesothelin (MSLN) (AA 37-286) antibody
MSLN Reactivity: Human, Mouse ELISA, WB, FACS Host: Mouse Monoclonal 5C11A4 unconjugated

anti-Mesothelin (MSLN) (AA 296-580) antibody
MSLN Reactivity: Human ELISA, FACS Host: Rabbit Monoclonal DM71 unconjugated Recombinant Antibody

anti-Mesothelin (MSLN) (AA 273-407) antibody
MSLN Reactivity: Human IHC (f) Host: Mouse Monoclonal unconjugated

anti-Mesothelin (MSLN) (AA 37-598) antibody
MSLN Reactivity: Human ELISA, IHC, IP, IF Host: Rabbit Polyclonal unconjugated

anti-Mesothelin (MSLN) (AA 296-606) antibody
MSLN Reactivity: Human, Mouse ELISA, WB Host: Mouse Monoclonal 7E6A6 unconjugated

anti-Mesothelin (MSLN) (Extracellular), (Extracellular Domain) antibody
MSLN Reactivity: Human WB, IHC Host: Mouse Monoclonal MB-G10 unconjugated

anti-Mesothelin (MSLN) (Extracellular Domain) antibody
MSLN Reactivity: Human WB, IHC Host: Mouse Monoclonal MN-1 unconjugated

anti-Mesothelin (MSLN) (AA 273-407) antibody (Biotin)
MSLN Reactivity: Human IHC (f) Host: Mouse Monoclonal Biotin

anti-Mesothelin (MSLN) (AA 1-62) antibody
MSLN Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Positive Control: CAPAN-2 or HeLa cells. Lung Mesothelioma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Restrictions

For Research Use only
Concentration

200 μg/mL

Buffer

Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-80 °C

Storage Comment

Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Expiry Date

24 months
Target

Mesothelin (MSLN)

Alternative Name

MSLN (MSLN Products)

Synonyms

MPF antibody, SMRP antibody, MSLN antibody, mesothelin antibody, MSLN antibody, Msln antibody, LOC611363 antibody, LOC100524016 antibody

Background

CAK1, Megakaryocyte potentiating factor, Mesothelin, MSLN, SMR, SMRP,Mesothelin (Mesothelial Marker)
Cellular localisation: Cell Surface and Secreted

Molecular Weight

40kDa (Mature form), 69kDa (Precursor)

Gene ID

10232, 408488

UniProt

Q13421

Pathways

EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process