CALCOCO2 antibody (AA 137-446)
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- Target See all CALCOCO2 Antibodies
- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
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Binding Specificity
- AA 137-446
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CALCOCO2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Calcium-binding and coiled-coil domain-containing protein 2 protein (137-446AA)
- Isotype
- IgG
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anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibody
CALCOCO2 Reactivity: Human WB, IF, ELISA Host: Mouse Monoclonal 2A11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 Reactivity: Human, Rat, Monkey, Dog WB, IF, FACS Host: Mouse Monoclonal 2D11 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (Internal Region) antibodyCALCOCO2 Reactivity: Human, Mouse, Rat WB, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 347-446) antibodyCALCOCO2 Reactivity: Human WB, IF, ELISA Host: Mouse Monoclonal 3C4 unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 1-446) antibodyCALCOCO2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) (AA 137-446) antibodyCALCOCO2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2) antibodyCALCOCO2 Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CALCOCO2 (Calcium Binding and Coiled-Coil Domain 2 (CALCOCO2))
- Alternative Name
- CALCOCO2 (CALCOCO2 Products)
- Synonyms
- CALCOCO2 antibody, MGC110205 antibody, wu:fj08c01 antibody, zgc:110205 antibody, DKFZp469D2219 antibody, NDP52 antibody, 2410154J16Rik antibody, C77254 antibody, Ndp52 antibody, Ndp52l1 antibody, RGD1559974 antibody, calcium binding and coiled-coil domain 2 antibody, CALCOCO2 antibody, calcoco2 antibody, Calcoco2 antibody
- Background
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Background: Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation. Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens such as Salmonella typhimurium upon entry into the cytosol by targeting galectin-8-associated bacteria for autophagy (PubMed:22246324). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen-containing autophagosome maturation (PubMed:23022382, PubMed:25771791). Bacteria targeting to autophagosomes relies on its interaction with MAP1LC3A, MAP1LC3B and/or GABARAPL2, whereas regulation of pathogen-containing autophagosome maturation requires the interaction with MAP3LC3C (PubMed:23022382, PubMed:25771791). May play a role in ruffle formation and actin cytoskeleton organization and seems to negatively regulate constitutive secretion (PubMed:17635994).
Aliases: Antigen nuclear dot 52 kDa protein antibody, CACO2_HUMAN antibody, Calcium binding and coiled coil domain 2 antibody, Calcium binding and coiled coil domain containing protein 2 antibody, Calcium-binding and coiled-coil domain-containing protein 2 antibody, CALCOCO 2 antibody, CALCOCO2 antibody, MGC17318 antibody, NDP52 antibody, Nuclear domain 10 protein 52 antibody, Nuclear domain 10 protein antibody, Nuclear domain 10 protein NDP52 antibody, Nuclear domain protein 52 antibody, Nuclear dot protein 52 antibody, OTTHUMP00000218344 antibody, OTTHUMP00000218345 antibody, OTTHUMP00000218346 antibody, OTTHUMP00000218347 antibody, OTTHUMP00000218349 antibody, OTTHUMP00000218351 antibody
- UniProt
- Q13137
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