For best experience we recommend to activate Javascript in your browser.

BBS4 antibody (AA 1-240)

Name: BBS4 antibody (AA 1-240)
SKU: ABIN1882046
Price: 429 USD
Availability: InStock

BBS4 Reactivity: Human, Mouse, Rat WB Host: Mouse Monoclonal 1292CT845-130-218 unconjugated

Western blot analysis of lysates from Hela, cell line, mouse heart and kidney, rat heart and kidney tissue (from left to right), using PHB Antibody (ABIN1882046 and ABIN2838486).

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 am2250b.

IHC

2 images

(1 reference)

Catalog No. ABIN1882046

Datasheet as PDF

Target See all BBS4 Antibodies

BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
Binding Specificity
15

4

2

2

1

1

1

1

1

1

1
AA 1-240
Reactivity
23

18

6

3

3

2

2

2

2

2

2

1
Human, Mouse, Rat
Host
27

4

2
Mouse
Compatible Secondaries
Clonality
31

2
Monoclonal
Conjugate
19

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This BBS4 antibody is un-conjugated
Application
33

13

13

8

4

4

3

2

2

1

1
Western Blotting (WB)

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This BBS4 antibody is generated from a mice immunized with a recombinant protein between 1-240 amino acids from human BBS4.

Clone

1292CT845-130-218

Isotype

IgG1

Top Product

Discover our top product BBS4 Primary Antibody
anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 350-519) antibody
BBS4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibody
BBS4 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 431-519) antibody
BBS4 Reactivity: Mouse WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 337-369) antibody
BBS4 Reactivity: Human WB Host: Rabbit Polyclonal RB14682 unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (N-Term) antibody
BBS4 Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig WB Host: Rabbit Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 33-46) antibody
Verified BBS4 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 125-139) antibody
Verified BBS4 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 1-519) antibody
BBS4 Reactivity: Human WB Host: Mouse Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 215-264) antibody
BBS4 Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Zebrafish (Danio rerio), Monkey, Bat WB Host: Rabbit Polyclonal unconjugated

anti-Bardet-Biedl Syndrome 4 (BBS4) (AA 71-120) antibody
BBS4 Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated

Application Notes

IHC: 1:250. WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Badano, Leitch, Ansley, May-Simera, Lawson, Lewis, Beales, Dietz, Fisher, Katsanis: "Dissection of epistasis in oligogenic Bardet-Biedl syndrome." in: Nature, Vol. 439, Issue 7074, pp. 326-30, (2006) (PubMed).
Target

BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

Alternative Name

BBS4 (BBS4 Products)

Synonyms

CG13232 antibody, Dmel\\CG13232 antibody, zgc:152964 antibody, AW537059 antibody, AW742241 antibody, D9Ertd464e antibody, Bardet-Biedl syndrome 4 antibody, bardet-biedl syndrome 4 antibody, Bardet-Biedl syndrome 4 (human) antibody, BBS4 antibody, bbs4 antibody, Bbs4 antibody

Background

The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization. Required for microtubule anchoring at the centrosome but not for microtubule nucleation. May be required for the dynein-mediated transport of pericentriolar proteins to the centrosome.

Molecular Weight

58282

UniProt

Q96RK4

Pathways

Hedgehog Signaling, Tube Formation, Maintenance of Protein Location