TCIRG1 antibody (AA 1-130)
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- Target See all TCIRG1 Antibodies
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
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Binding Specificity
- AA 1-130
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCIRG1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purpose
- TCIRG1 Rabbit pAb
- Sequence
- MGSMFRSEEV ALVQLFLPTA AAYTCVSRLG ELGLVEFRDL NASVSAFQRR FVVDVRRCEE LEKTFTFLQE EVRRAGLVLP PPKGRLPAPP PRDLLRIQEE TERLAQELRD VRGNQQALRA QLHQLQLHAA
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human TCIRG1 (NP_006010.2).
- Isotype
- IgG
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anti-T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1) (AA 76-182), (Isoform 3) antibody
TCIRG1 Reactivity: Human ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1) (AA 668-702) antibodyTCIRG1 Reactivity: Mouse WB, FACS Host: Rabbit Polyclonal RB57390 unconjugated
anti-T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1) (AA 121-220) antibodyTCIRG1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 6H3 unconjugated
anti-T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1) (AA 121-220) antibodyTCIRG1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 7H20 unconjugated
anti-T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1) (AA 1-614) antibodyTCIRG1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TCIRG1 (T-Cell, Immune Regulator 1, ATPase, H+ Transporting, Lysosomal V0 Subunit A3 (TCIRG1))
- Alternative Name
- TCIRG1 (TCIRG1 Products)
- Synonyms
- OC116 antibody, TIRC7 antibody, ATP6N1C antibody, ATP6a3 antibody, Atp6i antibody, OC-116 antibody, OPTB1 antibody, Stv1 antibody, Vph1 antibody, oc antibody, ATP6V0A3 antibody, OC-116kDa antibody, a3 antibody, T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 antibody, T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 antibody, T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3 antibody, Tcirg1 antibody, TCIRG1 antibody
- Background
- This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.,TCIRG1,ATP6N1C,ATP6V0A3,Atp6i,OC-116 kDa,OC116,OPTB1,Stv1,TIRC7,Vph1,a3,Signal Transduction,Endocrine & Metabolism,TCIRG1
- Molecular Weight
- 68kDa/92kDa
- Gene ID
- 10312
- UniProt
- Q13488
- Pathways
- Transition Metal Ion Homeostasis, Proton Transport
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