TNIP1 antibody
(1 reference)-
- Target See all TNIP1 Antibodies
- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNIP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TNIP1
- Isotype
- IgG
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anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 526-636) antibody
TNIP1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB28148 unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) antibodyTNIP1 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 1-636) antibodyTNIP1 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 99-148) antibodyTNIP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (C-Term) antibodyTNIP1 Reactivity: Human, Horse, Dog WB Host: Rabbit Polyclonal unconjugated
anti-TNFAIP3 Interacting Protein 1 (TNIP1) (AA 454-482), (C-Term) antibodyTNIP1 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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: "A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6980398, (2020) (PubMed).
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: "A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6980398, (2020) (PubMed).
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- Target
- TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))
- Alternative Name
- TNIP1 (TNIP1 Products)
- Synonyms
- ABIN-1 antibody, NAF1 antibody, VAN antibody, nip40-1 antibody, ABIN antibody, ABIN1 antibody, AU018810 antibody, Naf1 antibody, Nef antibody, im:7141452 antibody, naf1 antibody, zgc:158159 antibody, tnip1 antibody, MGC147597 antibody, TNFAIP3 interacting protein 1 antibody, TNFAIP3 interacting protein 1 S homeolog antibody, TNFAIP3-interacting protein 1 antibody, TNIP1 antibody, Tnip1 antibody, tnip1 antibody, tnip1.S antibody, LOC100078195 antibody
- Background
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Synonyms: ABIN 1, ABIN-1, abin1, HIV-1 Nef interacting protein Nip40-1, TNFAIP3 interacting protein 1, HIV-1 Nef interacting protein, HIV-1 Nef-interacting protein, hVAN, KIAA0113, NAF 1, NAF-1, NAF1, Nef-associated factor 1, Nef-associated factor 1 SNP, Nip 40-1, Nip40-1, TNFAIP3 interacting protein 1, TNFAIP3-interacting protein 1, TNIP 1, TNIP-1, Tnip1, TNIP1_HUMAN, VAN, Virion associated nuclear shuttling protein, Virion-associated nuclear shuttling protein.
Background: Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NF_B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.
- Pathways
- Activation of Innate immune Response
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