HYOU1 antibody
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- Target See all HYOU1 Antibodies
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HYOU1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human HYOU1 (NP_001124463.1).
- Isotype
- IgG
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anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibody
HYOU1 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibodyHYOU1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibodyHYOU1 Reactivity: Human, Rat WB, IHC, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 274-303) antibodyHYOU1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB18634 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 1-140) antibodyHYOU1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (HRP)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 HRP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (FITC)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 FITC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (Biotin)HYOU1 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 6E3-2C3 Biotin
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
- Alternative Name
- HYOU1 (HYOU1 Products)
- Synonyms
- GRP-170 antibody, Grp170 antibody, HSP12A antibody, ORP-150 antibody, ORP150 antibody, AI415631 antibody, CBP-140 antibody, Cab140 antibody, Orp150 antibody, id:ibd5056 antibody, wu:fd14c05 antibody, zgc:56019 antibody, HYOU1 antibody, orp150 antibody, GRP170 antibody, hypoxia up-regulated 1 antibody, hypoxia up-regulated protein 1 antibody, hypoxia up-regulated 1 S homeolog antibody, HYOU1 antibody, Hyou1 antibody, hyou1 antibody, LOC100380749 antibody, hyou1.S antibody
- Background
- The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants.
- Gene ID
- 10525
- UniProt
- Q9Y4L1
- Pathways
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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