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TXNIP antibody (AA 1-166)

TXNIP Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6149733
  • Target See all TXNIP Antibodies
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Binding Specificity
    • 16
    • 14
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-166
    Reactivity
    • 62
    • 47
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 71
    • 5
    Rabbit
    Clonality
    • 62
    • 14
    Polyclonal
    Conjugate
    • 31
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is un-conjugated
    Application
    • 58
    • 32
    • 16
    • 14
    • 14
    • 8
    • 8
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS QQCKQTSEYL RYEDTLLLED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEK
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human TXNIP (NP_006463.3).
    Isotype
    IgG
    Top Product
    Discover our top product TXNIP Primary Antibody
  • Application Notes
    WB,1:200 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zhang, Zhang, Deng, Zhang, Xu: "Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation." in: Chemico-biological interactions, Vol. 278, pp. 189-196, (2017) (PubMed).

  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Alternative Name
    TXNIP (TXNIP Products)
    Synonyms
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    Background
    This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.,TXNIP,ARRDC6,EST01027,HHCPA78,THIF,VDUP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Carbohydrate metabolism,TXNIP
    Molecular Weight
    37 kDa/43 kDa
    Gene ID
    10628
    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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