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KIF1C antibody

KIF1C Reactivity: Human, Rat, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7241606
  • Target See all KIF1C Antibodies
    KIF1C (Kinesin Family Member 1C (KIF1C))
    Reactivity
    • 23
    • 18
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 26
    • 2
    Rabbit
    Clonality
    • 26
    • 2
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIF1C antibody is un-conjugated
    Application
    • 16
    • 9
    • 7
    • 3
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human KIF1C
    Isotype
    IgG
  • Application Notes
    WB 1:200-1:1000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KIF1C (Kinesin Family Member 1C (KIF1C))
    Alternative Name
    KIF1C (KIF1C Products)
    Synonyms
    KIF1C antibody, ltxs1 antibody, DKFZp468E0822 antibody, LTXS1 antibody, B430105J22Rik antibody, D11Bwg1349e antibody, Ltxs1 antibody, kinesin family member 1C antibody, KIF1C antibody, kif1c antibody, Kif1c antibody
    Background
    The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
    Molecular Weight
    123 kDa
    UniProt
    O43896
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