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CTH antibody

CTH Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387469
  • Target See all CTH Antibodies
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    Reactivity
    • 54
    • 28
    • 28
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 48
    • 10
    Rabbit
    Clonality
    • 48
    • 10
    Polyclonal
    Conjugate
    • 35
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTH antibody is un-conjugated
    Application
    • 48
    • 16
    • 12
    • 11
    • 10
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase
    Isotype
    IgG
    Top Product
    Discover our top product CTH Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Shiina, Shima, Horii, Naitou, Nakamori, Sano, Shimizu: "Inhibitory action of hydrogen sulfide on esophageal striated muscle motility in rats." in: European journal of pharmacology, Vol. 771, pp. 123-9, (2016) (PubMed).

  • Target
    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
    Alternative Name
    CTH (CTH Products)
    Synonyms
    DYT17 antibody, DYT18 antibody, DYT9 antibody, EIG12 antibody, GLUT antibody, GLUT1 antibody, GLUT1DS antibody, HTLVR antibody, PED antibody, wu:fb48e03 antibody, wu:fb58d08 antibody, zgc:66001 antibody, zgc:85785 antibody, CTH antibody, 0610010I13Rik antibody, AI314617 antibody, BC019483 antibody, CSE antibody, Cys3 antibody, cysA antibody, SCQ11.03c antibody, DDBDRAFT_0190313 antibody, DDBDRAFT_0191318 antibody, DDB_0190313 antibody, DDB_0191318 antibody, H antibody, MGC75946 antibody, cystathionine gamma-lyase antibody, solute carrier family 2 member 1 antibody, cystathionase (cystathionine gamma-lyase) antibody, cystathionine gamma-lyase L homeolog antibody, CTH antibody, SLC2A1 antibody, cth antibody, Cth antibody, SCO3920 antibody, mlr1566 antibody, TA_RS00415 antibody, MAP_RS15640 antibody, SPO3344 antibody, CNN01730 antibody, Mmcs_1928 antibody, RHA1_RS31820 antibody, HNE_1212 antibody, MAV_3867 antibody, MSMEG_2394 antibody, Mvan_2142 antibody, SACE_6136 antibody, Mflv_4220 antibody, cysA antibody, cth.L antibody
    Background

    Synonyms: CGL_HUMAN, CTH, Cystathionine gamma lyase, Cystathionine gamma-lyase, Cysteine desulfhydrase, Gamma cystathionase, Gamma-cystathionase, Homoserine deaminase, Homoserine dehydratase, MGC9471, CSE, Cystathionase.

    Background: Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.

    Gene ID
    1491
    Pathways
    ER-Nucleus Signaling, Warburg Effect
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