JMJD1C antibody (N-Term)
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- Target See all JMJD1C Antibodies
- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This JMJD1C antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects JMJD1C / TRIP8. It will not cross-react with JMJD1A or JMJD1B.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogen
- JMJD1C antibody was raised against a 20 amino acid peptide from near the amino terminus of human JMJD1C.
- Isotype
- IgG
- Top Product
- Discover our top product JMJD1C Primary Antibody
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anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibody
JMJD1C Reactivity: Human ELISA, WB, IHC (p) Host: Mouse Monoclonal 5F12 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 539-648) antibodyJMJD1C Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2-99) antibodyJMJD1C Reactivity: Human ELISA, WB Host: Mouse Monoclonal 3A8 unconjugated
anti-Jumonji Domain Containing 1C (JMJD1C) (AA 2019-2051) antibodyJMJD1C Reactivity: Human WB Host: Rabbit Polyclonal RB55072 unconjugated
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- Application Notes
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- JMJD1C (Jumonji Domain Containing 1C (JMJD1C))
- Alternative Name
- JMJD1C / TRIP8 (JMJD1C Products)
- Synonyms
- RP11-10C13.2 antibody, TRIP8 antibody, 5430433L24Rik antibody, D630035I23Rik antibody, Jmjdic antibody, Pr2 antibody, JMJD1C antibody, DKFZp469A034 antibody, jumonji domain containing 1C antibody, JMJD1C antibody, Jmjd1c antibody, jmjd1c antibody
- Background
- The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU5F1-mediated expression of JMJD1C reactivates previously silenced genes in ES cells and diffuse-type gastric cancer. At least three isoforms of JMJD1C are known to exist.Synonyms: JHDM2C, Jumonji domain-containing protein 1C, KIAA1380, Probable JmjC domain-containing histone demethylation protein 2C, Thyroid receptor-interacting protein 8
- Gene ID
- 221037
- NCBI Accession
- NP_116165
- UniProt
- Q15652
- Pathways
- Nuclear Hormone Receptor Binding
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