ACTN1 antibody
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- Target See all ACTN1 Antibodies
- ACTN1 (Actinin, alpha 1 (ACTN1))
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Reactivity
- Human, Mouse, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ACTN1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ACTN1 (NP_001123477.1).
- Isotype
- IgG
- Top Product
- Discover our top product ACTN1 Primary Antibody
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anti-Actinin, alpha 1 (ACTN1) (AA 1-330) antibody
ACTN1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-30), (N-Term) antibodyACTN1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB21901 unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F1 unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 Reactivity: Human WB, IHC (p), IHC (wm) Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 Reactivity: Human IHC, ELISA Host: Mouse Monoclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 28-260) antibodyACTN1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-204) antibodyACTN1 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 Reactivity: Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ACTN1 (Actinin, alpha 1 (ACTN1))
- Alternative Name
- ACTN1 (ACTN1 Products)
- Background
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 105 kDa
Calculated_MW: 102 kDa/103 kDa/105 kDa/107 kDa
- Gene ID
- 87
- UniProt
- P12814
- Pathways
- Cell-Cell Junction Organization
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