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POLG2 antibody (AA 216-485)

POLG2 Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6145894
  • Target See all POLG2 Antibodies
    POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
    Binding Specificity
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 216-485
    Reactivity
    • 29
    • 9
    • 2
    • 1
    Human
    Host
    • 25
    • 4
    Rabbit
    Clonality
    • 27
    • 2
    Polyclonal
    Conjugate
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLG2 antibody is un-conjugated
    Application
    • 13
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    HPVFDTKQIR NGVKSIGEKT EASLVWFTPP RTSNQWLDFW LRHRLQWWRK FAMSPSNFSS SDCQDEEGRK GNKLYYNFPW GKELIETLWN LGDHELLHMY PGNVSKLHGR DGRKNVVPCV LSVNGDLDRG MLAYLYDSFQ LTENSFTRKK NLHRKVLKLH PCLAPIKVAL DVGRGPTLEL RQVCQGLFNE LLENGISVWP GYLETMQSSL EQLYSKYDEM SILFTVLVTE TTLENGLIHL RSRDTTMKEM MHISKLKDFL IKYISSAKNV
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2 (NP_009146.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:10 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
    Alternative Name
    POLG2 (POLG2 Products)
    Synonyms
    POLG2 antibody, im:7158733 antibody, si:ch211-157f15.3 antibody, HP55 antibody, MTPOLB antibody, PEOA4 antibody, POLB antibody, POLG-BETA antibody, POLGB antibody, mtpolb antibody, DNA polymerase gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit antibody, polymerase (DNA directed), gamma 2, accessory subunit L homeolog antibody, Polg2 antibody, POLG2 antibody, polg2 antibody, polg2.L antibody
    Background
    This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.,POLG2,HP55,MTPOLB,PEOA4,POLB,POLG-BETA,POLGB,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,POLG2
    Molecular Weight
    54 kDa
    Gene ID
    11232
    UniProt
    Q9UHN1
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