USP18 antibody (AA 200-300)
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- Target See all USP18 Antibodies
- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
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Binding Specificity
- AA 200-300
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This USP18 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purpose
- USP18 Rabbit pAb
- Sequence
- DVDSKPLKTL EDALHCFFQP RELSSKSKCF CENCGKKTRG KQVLKLTHLP QTLTIHLMRF SIRNSQTRKI CHSLYFPQSL DFSQILPMKR ESCDAEEQSG G
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human USP18 (NP_059110.2).
- Isotype
- IgG
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anti-Ubiquitin Specific Peptidase 18 (USP18) antibody
USP18 Reactivity: Human, Mouse, Rat WB, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 18-118), (C-Term) antibodyUSP18 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 1-372) antibodyUSP18 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (N-Term) antibodyUSP18 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 40-49) antibodyUSP18 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (AA 110-159) antibodyUSP18 Reactivity: Human, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 18 (USP18) (N-Term) antibodyUSP18 Reactivity: Human, Mouse, Dog, Rat, Horse, Cow, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- USP18 (Ubiquitin Specific Peptidase 18 (USP18))
- Alternative Name
- USP18 (USP18 Products)
- Synonyms
- ISG43 antibody, UBP43 antibody, bubp43 antibody, 1110058H21Rik antibody, AW047653 antibody, Ubp15 antibody, UBP antibody, USP18 antibody, USP41 antibody, ubiquitin specific peptidase 18 antibody, USP18 antibody, Usp18 antibody
- Background
- The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15.,USP18,ISG43,UBP43,PTORCH2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,USP18
- Molecular Weight
- 43kDa
- Gene ID
- 11274
- UniProt
- Q9UMW8
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