ABL2 antibody
(2 references)-
- Target See all ABL2 Antibodies
- ABL2
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ABL2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of ABL2 expressed in E. coli.
- Clone
- 1H1
- Isotype
- IgG1
- Top Product
- Discover our top product ABL2 Primary Antibody
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anti-ABL2 (ABL2) (AA 743-842) antibody
ABL2 Reactivity: Human WB, ELISA, PLA, RNAi Host: Mouse Monoclonal 6D5 unconjugated
anti-ABL2 (ABL2) (AA 743-842) antibodyABL2 Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 5C6 unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-ABL2 (ABL2) (pTyr393), (pTyr439) antibodyABL2 Reactivity: Human WB, IHC (p), DB Host: Rabbit Polyclonal RB7532 unconjugated
anti-ABL2 (ABL2) (AA 1011-1044), (C-Term) antibodyABL2 Reactivity: Mouse WB Host: Rabbit Polyclonal RB50829 unconjugated
anti-ABL2 (ABL2) (AA 862-1064) antibodyABL2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-ABL2 (ABL2) (AA 417-446) antibodyABL2 Reactivity: Human WB Host: Rabbit Polyclonal RB7532 unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-ABL2 (ABL2) antibodyABL2 Reactivity: Human, Mouse WB, IHC (p) Host: Mouse Monoclonal 2C3 unconjugated
anti-ABL2 (ABL2) (AA 1-1167) antibodyABL2 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." in: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).
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: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).
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- Target
- ABL2
- Alternative Name
- ABL2 (ABL2 Products)
- Synonyms
- ABLL antibody, ARG antibody, Abll antibody, Arg antibody, AA536808 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) antibody, ABL2 antibody, Abl2 antibody
- Background
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Description: ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89 % , 90 and 93 % identity in their SH3, SH2 and tyrosine domain, but only 29 % identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
Aliases: ARG, ABLL, FLJ22224, FLJ31718, FLJ41441
- Molecular Weight
- 128 kDa
- Gene ID
- 27
- HGNC
- 27
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