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CDK6 antibody

CDK6 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7259074
  • Target See all CDK6 Antibodies
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Reactivity
    • 126
    • 48
    • 25
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 109
    • 17
    Rabbit
    Clonality
    • 99
    • 27
    Polyclonal
    Conjugate
    • 67
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CDK6 antibody is un-conjugated
    Application
    • 76
    • 38
    • 29
    • 27
    • 27
    • 23
    • 23
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CDK6 (NP_001250.1).
    Isotype
    IgG
    Top Product
    Discover our top product CDK6 Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    Alternative Name
    CDK6 (CDK6 Products)
    Synonyms
    CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
    Background
    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.
    Gene ID
    1021
    UniProt
    Q00534
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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