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WDFY2 antibody (AA 2-114)

ZFYVE22 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7175695
  • Target See all WDFY2 (ZFYVE22) Antibodies
    WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))
    Binding Specificity
    • 3
    • 2
    • 1
    AA 2-114
    Reactivity
    • 15
    • 9
    • 1
    Human
    Host
    • 13
    • 2
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WDFY2 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human WD repeat and FYVE domain-containing protein 2 protein (2-114AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    WDFY2 (ZFYVE22) (Zinc Finger, FYVE Domain Containing 22 (ZFYVE22))
    Alternative Name
    WDFY2 (ZFYVE22 Products)
    Synonyms
    PROF antibody, RP11-147H23.1 antibody, WDF2 antibody, ZFYVE22 antibody, 5830485M08 antibody, B130024L21Rik antibody, ProF antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD repeat and FYVE domain containing 2 antibody, wdfy-2 antibody, WDFY2 antibody, Wdfy2 antibody
    Background

    Background: Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling, required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).

    Aliases: PROF antibody, Propeller-FYVE protein antibody, RP11 147H23.1 antibody, WD repeat and FYVE domain containing 2 antibody, WD repeat and FYVE domain-containing protein 2 antibody, WD40 and FYVE domain containing 2 antibody, WD40- and FYVE domain-containing protein 2 antibody, WDF2 antibody, Wdfy2 antibody, WDFY2_HUMAN antibody, ZFYVE22 antibody, Zinc finger FYVE domain-containing protein 22 antibody

    UniProt
    Q96P53
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