Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ALDH2 antibody (AA 317-517)

ALDH2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 4G6A3 unconjugated
Catalog No. ABIN1724795
  • Target See all ALDH2 Antibodies
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Binding Specificity
    • 10
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 317-517
    Reactivity
    • 78
    • 20
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 60
    • 16
    • 2
    Mouse
    Clonality
    • 59
    • 19
    Monoclonal
    Conjugate
    • 37
    • 10
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ALDH2 antibody is un-conjugated
    Application
    • 64
    • 42
    • 39
    • 16
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. coli.
    Clone
    4G6A3
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:150, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Zhang, Gong, Zhang, Li, Hu: "Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease." in: European heart journal, Vol. 33, Issue 13, pp. 1606-14, (2012) (PubMed).

    Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: "The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes." in: Clinical toxicology (Philadelphia, Pa.), Vol. 50, Issue 4, pp. 242-9, (2012) (PubMed).

  • Target
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Alternative Name
    ALDH2 (ALDH2 Products)
    Synonyms
    aldh2 antibody, aldh2a antibody, zgc:63786 antibody, MGC80785 antibody, aldh-e2 antibody, aldhi antibody, aldm antibody, rf2b antibody, ALDH-E2 antibody, ALDHI antibody, ALDM antibody, Ahd-5 antibody, Ahd5 antibody, aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 antibody, aldehyde dehydrogenase 2 family (mitochondrial) L homeolog antibody, aldehyde dehydrogenase 2 family (mitochondrial) antibody, aldehyde dehydrogenase 2 antibody, aldehyde dehydrogenase antibody, aldehyde dehydrogenase (NAD(+)) antibody, hypothetical protein antibody, aldehyde dehydrogenase 2, mitochondrial antibody, aldh2.1 antibody, aldh2.L antibody, aldh2 antibody, ALDH2 antibody, RHA1_RS43090 antibody, aldH2 antibody, OE_RS03015 antibody, Aldh2 antibody
    Background

    Description: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms. , , ,

    Aliases: ALDM, ALDHI, ALDH-E2

    Molecular Weight
    56.3 kDa
    Gene ID
    217
    HGNC
    217
You are here:
Support