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ALOX15B antibody (AA 13-110)

ALOX15B Reactivity: Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN873138
  • Target See all ALOX15B Antibodies
    ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))
    Binding Specificity
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 13-110
    Reactivity
    • 32
    • 20
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Rat
    Host
    • 45
    • 2
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALOX15B antibody is un-conjugated
    Application
    • 21
    • 13
    • 12
    • 12
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ALOX15B/15 Lipoxygenase 2
    Isotype
    IgG
    Top Product
    Discover our top product ALOX15B Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))
    Alternative Name
    ALOX15B (ALOX15B Products)
    Synonyms
    15-LOX-2 antibody, ALOX15B antibody, arachidonate 15-lipoxygenase, type B antibody, arachidonate 15-lipoxygenase B antibody, ALOX15B antibody, Alox15b antibody, LOC100525835 antibody
    Background

    Synonyms: 15-LOX-2, Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-lipoxygenase 2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-LOb, ALOX15B

    Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.

    Gene ID
    247
    UniProt
    O15296
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