ARC (Middle Region) antibody
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- Target
- ARC
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Cow, Goat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ELDLPQKQGE PLDQFLWRKR DLYQTLYVDA DEEEIIQYVV GTLQPKLKRF
- Predicted Reactivity
- Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ARC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ARC
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anti-ARC antibody
Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-ARC antibodyReactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-ARC (AA 1-396) antibodyReactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-ARC (AA 1-220) antibodyReactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-ARC (AA 191-208) antibodyReactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-ARC (AA 159-208) antibodyReactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-ARC (AA 37-66) antibodyReactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 396 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARC
- Synonyms
- activity regulated cytoskeleton associated protein antibody, Arc antibody
- Background
-
ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
Alias Symbols: KIAA0278, Arg3.1
Protein Interaction Partner: UBE3A, UBC, KRT15,
Protein Size: 396 - Molecular Weight
- 45 kDa
- Gene ID
- 23237
- NCBI Accession
- NM_015193, NP_056008
- UniProt
- Q7LC44
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