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Bcl-2 antibody (AA 101-160)

Name: Bcl-2 antibody (AA 101-160)
SKU: ABIN723920
Price: 384.62 USD
Availability: InStock

BCL2 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Chicken, Bacteria WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

Danshen-Chuanxiong-Honghua extract alleviated apoptosis and inhibited pro-inflammatory cytokine production in the injured hippocampus 24 h after cerebral ischemia and reperfusion.

Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-Bcl-2 Polyclonal Antibody, Unconjugated (ABIN723920) 1:400 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat myocardium tissue labeled with Anti-Bcl-2 Polyclonal Antibody, Unconjugated (ABIN723920) 1:300 followed by conjugation to the secondary antibody and DAB staining

IHC

Formalin-fixed and paraffin embedded rat kidney tissue labeled withAnti-Bcl-2 Polyclonal Antibody, Unconjugated (ABIN723920) 1:400 followed by conjugation to the secondary antibody and DAB staining

IHC

L1 mouse embryo lysates, L2 mouse brain lysates probed with Anti- Bcl-2 Polyclonal Antibody, Unconjugated (ABIN723920) at 1:200 in 4 °C.

SDS

5 images

(4 references)

Catalog No. ABIN723920

Datasheet as PDF

Target See all Bcl-2 (BCL2) Antibodies

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
Binding Specificity
51

34

23

22

21

18

17

16

16

15

15

14

13

10

8

8

8

8

7

7

7

6

6

6

6

6

6

5

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 101-160
Reactivity
443

183

178

37

34

22

21

17

16

15

10

5

5

1

1

1
Human, Mouse, Rat, Rabbit, Cow, Chicken, Bacteria
Host
356

111

6

2

1
Rabbit
Compatible Secondaries
Clonality
353

122
Polyclonal
Conjugate
209

34

34

25

24

15

11

11

11

11

11

11

9

9

9

9

9

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This Bcl-2 antibody is un-conjugated
Application
387

191

167

121

106

100

91

68

63

33

25

23

18

8

8

8

5

4

2

1

1

1

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity

Bacteria, Chicken, Cow, Human, Mouse, Rabbit, Rat

Predicted Reactivity

Dog,Cow,Pig,Horse

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from rat Bcl-2

Isotype

IgG

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BCL2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB04684 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibody
BCL2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 Reactivity: Human WB, FACS, IHC (p), IP, ICC, IHC (fro) Host: Mouse Monoclonal Bcl-2-100 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)
BCL2 Reactivity: Human FACS Host: Mouse Monoclonal Bcl-2-100 PE

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
She, Zhao, Zhu, Han, Xia, Bai, Zhang, Li: "Aluminum Trichloride Disorders Bile Acid Secretion and Induces Hepatocyte Apoptosis in Rats." in: Cell biochemistry and biophysics, (2015) (PubMed).

He, Song, Liu, Chen, Hua: "Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells." in: Cell proliferation, Vol. 47, Issue 2, pp. 161-71, (2014) (PubMed).

Tian, Zhang, Wang, Dai, Shen, Yang, Huang: "The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25-35-induced oxidative stress and neuronal apoptosis in rats." in: Behavioural brain research, Vol. 242, pp. 1-8, (2013) (PubMed).

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, (2012) (PubMed).
Target

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name

Bcl-2 (BCL2 Products)

Synonyms

Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody

Background

Synonyms: Bcl-2, Apoptosis regulator Bcl-2, Bcl2
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Gene ID

24224

UniProt

P49950

Pathways

MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling