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C4B antibody (AA 655-684)

C4b Reactivity: Human WB Host: Rabbit Polyclonal RB33642 unconjugated
Catalog No. ABIN657906
  • Target See all C4B (C4b) Antibodies
    C4B (C4b) (Complement Component C4b (C4b))
    Binding Specificity
    • 15
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 655-684
    Reactivity
    • 38
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 5
    • 3
    Rabbit
    Clonality
    • 52
    • 5
    Polyclonal
    Conjugate
    • 19
    • 8
    • 8
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C4B antibody is un-conjugated
    Application
    • 29
    • 24
    • 14
    • 13
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    H
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This C4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B.
    Clone
    RB33642
    Isotype
    Ig Fraction
    Top Product
    Discover our top product C4b Primary Antibody
  • Application Notes
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    C4B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    C4B (C4b) (Complement Component C4b (C4b))
    Alternative Name
    C4B (C4b Products)
    Synonyms
    C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, wu:fi14a03 antibody, C4B antibody, DKFZP469I0332 antibody, Slp antibody, Ss antibody, C4-2 antibody, C4l antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4 antibody, complement C4-B antibody, complement component 4B (Chido blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4B antibody, C4A antibody, c4 antibody, LOC462577 antibody, C4a antibody, C4b antibody
    Background
    This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
    Molecular Weight
    192785
    Gene ID
    721
    NCBI Accession
    NP_001002029, NP_001239133, NP_009224
    UniProt
    P0C0L4
    Pathways
    Complement System
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