SOCS4 antibody (AA 227-254)
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- Target See all SOCS4 Antibodies
- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
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Binding Specificity
- AA 227-254
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOCS4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 227-254 from the human protein was used as the immunogen for this SOCS4 antibody.
- Isotype
- Ig Fraction
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anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-270) antibody
SOCS4 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254) antibodySOCS4 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB31389 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodySOCS4 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2G8 unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodySOCS4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 234-262) antibodySOCS4 Reactivity: Human WB, IF, IHC (p), EIA, FACS Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (C-Term) antibodyVerified SOCS4 Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 1-440) antibodySOCS4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 4 (SOCS4) (AA 224-253) antibodySOCS4 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Titration of the SOCS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the SOCS4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))
- Alternative Name
- SOCS4 (SOCS4 Products)
- Synonyms
- SOCS7 antibody, socs4 antibody, SOCS4 antibody, 3110032M18Rik antibody, A730004F22Rik antibody, AI427843 antibody, AU015727 antibody, AU015859 antibody, Socs7 antibody, SOCS6 antibody, socs7 antibody, socs4a antibody, suppressor of cytokine signaling 4 antibody, SOCS4 antibody, socs4 antibody, Socs4 antibody
- Background
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR. [UniProt]
- UniProt
- Q8WXH5
- Pathways
- JAK-STAT Signaling, EGFR Signaling Pathway
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