NR1I3 antibody
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- Target See all NR1I3 Antibodies
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR1I3 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human NR1I3.
- Isotype
- IgG
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anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-351) antibody
NR1I3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (Internal Region) antibodyNR1I3 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 180-229) antibodyNR1I3 Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Pig, Horse, Rabbit, Monkey, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) antibodyNR1I3 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) antibodyNR1I3 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (C-Term) antibodyNR1I3 Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (N-Term) antibodyNR1I3 Reactivity: Human, Rat, Guinea Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 103-352) antibodyNR1I3 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (N-Term) antibodyNR1I3 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 245-294) antibodyNR1I3 Reactivity: Human, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- Alternative Name
- NR1I3 (NR1I3 Products)
- Synonyms
- AA209988 antibody, AI551208 antibody, CAR antibody, CAR-beta antibody, Care2 antibody, ESTM32 antibody, MB67 antibody, CAR1 antibody, CXR antibody, nuclear receptor subfamily 1 group I member 3 antibody, nuclear receptor subfamily 1, group I, member 3 antibody, NR1I3 antibody, Nr1i3 antibody
- Background
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene ID
- 9970
- UniProt
- Q14994
- Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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