CCR8 Protein (AA 1-35) (mFc Tag)
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- Target See all CCR8 Proteins
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-35
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR8 protein is labelled with mFc Tag.
- Purpose
- Human CCR8 Protein
- Sequence
- Met1-Lys35
- Characteristics
- Recombinant Human CCR8 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Met1-Lys35.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CCR8, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA. See testing image for detail.
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Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 1-35) protein (Fc Tag)
CCR8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 1-355) protein (GST tag)CCR8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 1-355) protein (Strep Tag)Crystallography grade CCR8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 1-353) protein (Strep Tag)Crystallography grade CCR8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- Alternative Name
- CCR8 (CCR8 Products)
- Synonyms
- CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein
- Background
- CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
- Molecular Weight
- 30.25 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
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