CBX1 antibody (Center)
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- Target See all CBX1 Antibodies
- CBX1 (Chromobox Homolog 1 (CBX1))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CBX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Cross-Reactivity
- Cow (Bovine), Chicken, Chimpanzee
- Cross-Reactivity (Details)
- Chicken (85 %), Chimpanzee (100 %), Bovine (100 %)
- Characteristics
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Rabbit Polyclonal antibody to CBX1 / HP1 beta (chromobox homolog 1)
CBX1 / HP1 beta antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CBX1 / HP1 beta. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CBX1 Primary Antibody
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anti-Chromobox Homolog 1 (CBX1) (AA 1-185) antibody
CBX1 Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 4D7B8 unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 2-99) antibodyCBX1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4E12 unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 128-155), (C-Term) antibodyCBX1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB23535 unconjugated
anti-Chromobox Homolog 1 (CBX1) (Internal Region) antibodyVerified CBX1 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 176-185) antibodyCBX1 Reactivity: Human, Hamster WB, IF, ChIP Host: Rabbit Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 1-185) antibodyCBX1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (AA 176-185) antibodyCBX1 Reactivity: Human, Hamster WB, IF, ChIP-seq Host: Rabbit Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) (N-Term) antibodyCBX1 Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) antibodyCBX1 Reactivity: Human WB, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Chromobox Homolog 1 (CBX1) antibodyCBX1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Comment
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Positive Control: Raji
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CBX1 (Chromobox Homolog 1 (CBX1))
- Alternative Name
- CBX1 / HP1 beta (CBX1 Products)
- Synonyms
- CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, Cbx antibody, Cbx-rs2 antibody, E430007M08Rik antibody, HP1B antibody, Hp1beta antibody, cbx1 antibody, wu:fe14b09 antibody, zgc:55739 antibody, zgc:86924 antibody, chromobox 1 antibody, chromobox homolog 1a (HP1 beta homolog Drosophila) antibody, chromobox 1 S homeolog antibody, chromobox homolog 1b (HP1 beta homolog Drosophila) antibody, CBX1 antibody, Cbx1 antibody, cbx1a antibody, cbx1.S antibody, cbx1b antibody
- Background
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This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Cellular Localization: Nucleus - Molecular Weight
- 21 kDa
- Gene ID
- 10951
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