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CTLA4 antibody (AA 75-170)

Name: CTLA4 antibody (AA 75-170)
SKU: ABIN1714514
Price: 384.62 USD
Availability: InStock

CTLA4 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated

Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000; TMB staining Read the data in Microplate Reader by 450nm.

ELISA

Mouse lung lysate probed with Anti CTLA4 Polyclonal Antibody, Unconjugated (ABIN1714514) at 1:200 overnight at 4 °C.

SDS

2 images

(2 references)

Catalog No. ABIN1714514

Datasheet as PDF

Target See all CTLA4 Antibodies

CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
Binding Specificity
15

12

6

6

6

6

2

2

2

2

1

1

1

1

1

1

1

1
AA 75-170
Reactivity
90

59

34

5

4
Human, Mouse, Rat
Host
61

47

13

10

1

1
Rabbit
Compatible Secondaries
Clonality
77

53

2
Polyclonal
Conjugate
63

15

13

12

6

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CTLA4 antibody is un-conjugated
Application
79

64

51

33

17

17

14

12

10

7

6

5

5

4

3

2

2

2
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity

Human, Mouse, Rat

Predicted Reactivity

Dog,Cow,Sheep,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human CTLA-4/CD152

Isotype

IgG

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CTLA4 Reactivity: Human FACS Host: Mouse Monoclonal BNI3 PE

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CTLA4 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2F1 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody
CTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody
CTLA4 Reactivity: Human FACS, IP, ICC, IHC (fro) Host: Mouse Monoclonal BNI3 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibody
CTLA4 Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 9D2E9 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibody
CTLA4 Reactivity: Human FACS, WB, ELISA, IHC, ICC, Neut Host: Mouse Monoclonal 8B3F8 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibody
CTLA4 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibody
CTLA4 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 50-78) antibody
CTLA4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB23352 unconjugated

anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody (APC)
CTLA4 Reactivity: Human FACS Host: Mouse Monoclonal BNI3 APC

Application Notes

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Schlößer, Drebber, Kloth, Thelen, Rothschild, Haase, Garcia-Marquez, Wennhold, Berlth, Urbanski, Alakus, Schauss, Shimabukuro-Vornhagen, Theurich, Warnecke-Ebertz, Stippel, Zippelius, Büttner, Hallek et al.: "Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. ..." in: Oncoimmunology, Vol. 5, Issue 5, pp. e1100789, (2016) (PubMed).

Tamaka, Seike, Hagiwara, Sato, Ohtsu: "Histamine suppresses regulatory T cells mediated by TGF-? in murine chronic allergic contact dermatitis." in: Experimental dermatology, Vol. 24, Issue 4, pp. 280-4, (2015) (PubMed).
Target

CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Alternative Name

CTLA4 (CTLA4 Products)

Synonyms

CTLA-4 antibody, CTLA4 antibody, CD152 antibody, Cd152 antibody, Ctla-4 antibody, Ly-56 antibody, CD antibody, CELIAC3 antibody, GRD4 antibody, GSE antibody, IDDM12 antibody, sCTLA4 antibody, cytotoxic T-lymphocyte associated protein 4 antibody, cytotoxic T-lymphocyte-associated protein 4 antibody, CTLA4 antibody, Ctla4 antibody

Background

Synonyms: CD, GSE, GRD4, CD152, CTLA-4, IDDM12, CELIAC3, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA4
Background: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Gene ID

1493

UniProt

P16410

Pathways

Cancer Immune Checkpoints