OSCAR Protein (AA 19-229) (Fc Tag)
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- Target See all OSCAR Proteins
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-229
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OSCAR protein is labelled with Fc Tag.
- Purpose
- Human OSCAR Protein
- Sequence
- Asp19-Ser229
- Characteristics
- Recombinant Human OSCAR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp19-Ser229.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human OSCAR, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-OSCAR Antibody, hFc Tag with the EC50 19.2ng/ml determined by ELISA. See testing image for detail.
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Osteoclast Associated Receptor (OSCAR) (AA 19-228) protein (Fc Tag)
OSCAR Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Osteoclast Associated Receptor (OSCAR) (AA 175-254) protein (GST tag)OSCAR Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Osteoclast Associated Receptor (OSCAR) (AA 19-282) protein (His tag)Crystallography grade OSCAR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Osteoclast Associated Receptor (OSCAR) (AA 19-231) protein (His tag)Crystallography grade OSCAR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Osteoclast Associated Receptor (OSCAR) (AA 19-265) protein (rho-1D4 tag)Crystallography grade OSCAR Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Osteoclast Associated Receptor (OSCAR) (AA 19-286) protein (His tag)OSCAR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Osteoclast Associated Receptor (OSCAR) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)OSCAR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- OSCAR (Osteoclast Associated Receptor (OSCAR))
- Alternative Name
- OSCAR (OSCAR Products)
- Synonyms
- OSCAR Protein, mOSCAR-M3 Protein, mOSCAR Protein, mOSCAR-M1 Protein, mOSCAR-M2 Protein, PIGR3 Protein, PIgR-3 Protein, RGD1559897 Protein, osteoclast associated, immunoglobulin-like receptor Protein, osteoclast-associated immunoglobulin-like receptor Protein, osteoclast associated receptor Protein, OSCAR Protein, LOC748876 Protein, Oscar Protein
- Background
- Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA.
- Molecular Weight
- 49.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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